PAIN
Chronic Pain? Melatonin May Provide Some Relief, Study Finds: A new study found melatonin eased chronic musculoskeletal pain about as effectively as over-the-counter painkillers. The benefit was clearest for chronic pain, but results for post-surgical pain were less clear, the study found. The study reported that melatonin is safe in the short term at low doses, defined as less than 3 months and less than 5 milligrams. Experts advise talking with a doctor before trying melatonin for pain, particularly if you don’t currently have trouble sleeping or take other medications. PAIN
Could acupuncture to the ear help to relieve migraines? Acupuncture to the ear may help to lessen pain from migraines and their impact on daily life, according to new research presented at the Federation of European Neuroscience Societies (FENS) Forum 2026 [1]. A randomised clinical trial of the treatment, called auriculotherapy, found that migraines were less painful immediately after the treatment and 30 days later, compared with the pain experienced before treatment. The impact of migraines on daily life also improved. In addition, the researchers observed changes in oxygenation levels in the prefrontal cortex of the brain over the course of the study, as measured by hemoencephalography (HEG®), which is a non-invasive technology using near-infrared spectroscopy to measure blood flow in the brain, and is an indirect measure of neural activity.
Many chronic pain patients can reduce opioid use with slow, voluntary taper: A new large-scale study led by Stanford Medicine suggests that — with the right approach — many people may be able to reduce their opioid use long term without increasing their pain. The key is a gradual approach to tapering opioid doses that puts the patient in the driver’s seat. “So much of the fear of opioid tapering is about losing control,” said Beth Darnall, PhD, a professor of anesthesiology, perioperative and pain medicine and lead author of the studypublished July 7 in the Annals of Internal Medicine. “We tested a patient-centered methodology where we really focused on the individual patient and developed methods to ensure that they had maximal control in the process.”
When back pain won't quit: A large clinical trial points to the power of self-management: A randomized clinical trial published June 1, 2026, in JAMA Internal Medicine found that a personalized self-management program — delivered by physical therapists and chiropractors — was more effective at preventing the conversion to high impact chronic low back pain than standard medical care or hands-on spinal manipulation alone.
Mindfulness-based group medical visits for persons with chronic low back pain: In this randomized clinical trial, a telehealth-delivered mindfulness group medical visit program for persons with chronic low back pain (CLBP) resulted in significant improvements in pain intensity and interference compared with usual care; however, these changes did not meet the prespecified mean 1-point minimal clinically important difference between groups. The program incorporated primary care clinicians, was accessible, and is potentially scalable as a nonpharmacologic treatment for CLBP. published in JAMA Internal Medicine,
Self-directed vs clinician-delivered cognitive behavioral therapy for chronic pain: Self-directed cognitive behavioral therapy for chronic pain (CBT-CP) was associated with modest improvements in pain interference at 4 months that were sustained to 12 months, small to moderate improvements in all secondary outcomes at 4 months, and higher session-completion rates, relative to clinician-delivered CBT-CP. Scalable, convenient self-directed CBT may be an effective alternative to clinician-delivered CBT that could increase uptake of CBT-CP. JAMA
Persistent herpes zoster-associated pain: New review uncovers mechanisms and supports earlier intervention: For millions worldwide, herpes zoster pain does not end when the rash fades. Postherpetic neuralgia can last for years or even a lifetime, devastating quality of life. Now, a comprehensive review led by Professor Bifa Fan from China–Japan Friendship Hospital has mapped the full cascade of mechanisms driving this persistent pain, providing definitive support for earlier, more aggressive treatment.
From loss to purpose: How new goals can improve life with chronic pain: New research from Edith Cowan University (ECU) has found that people living with chronic pain can protect their mental wellbeing by focusing on new, meaningful goals, rather than simply trying to let go of old ones. Psychological Applications and Trends.
Nonsurgical procedure provides lasting relief for knee pain: Embolization of abnormal blood vessels using rapidly resorbable gelatin-based microspheres is safe and provides significant, lasting pain relief and functional improvement for patients with osteoarthritis-related knee pain, according to a new study published today in Radiology, a journal of the Radiological Society of North America (RSNA).
Common dizziness drug class shows promise for treating vestibular migraine: A new study finds that a class of oral and intranasal medications known as gepants may be an effective and well-tolerated treatment for vestibular migraine (VM). Otolaryngology
COMPLEMENTARY AND ALTERNATIVE MEDICINE
Heavy marijuana smoking may increase cancer risk, researchers warn: Heavy marijuana smoking may raise the risk of lung cancer and several head and neck cancers, according to growing research, but many important questions remain unanswered. Scientists are still trying to determine how much marijuana use is enough to significantly increase cancer risk. Edibles have not been linked to lung cancer so far, while the long-term effects of vaping marijuana and secondhand marijuana smoke are still being investigated.
FDA APPROVALS
• Approved Trutakna, a self-administered injectable treatment approved for patients with immunoglobulin A nephropathy, also known as Berger's disease, which causes abnormal protein buildup in the kidneys and could eventually lead to the organ's failure.
• Approved, Lipfendra (enlicitide) for the treatment of a form of heritable high cholesterol.
• Expands Use of Zoryve to Include Young Children With Plaque Psoriasis
• Expands Use of First Sickle Cell Disease Gene Therapy for Children as Young as 2 Years
• Approved Lumvoa for Both Active and Chronic Thyroid Eye Disease
• Approved Tzield for Children With New Stage 3 Type 1 Diabetes
• Approved Oral Utebzi Antibiotic for Complicated Urinary Tract Infections
• Approved Welireg With Pembrolizumab for Renal Cell Carcinoma
PREVENTION: Exercise
Sniffing Chocolate Could Boost Your Leg Day Workouts and Curb Hunger: Smelling dark chocolate before and during a leg workout helped participants perform more repetitions. Though the exact mechanism remains unclear, researchers suspect that certain scents trigger physiological changes that may affect physical performance. Other scents, including peppermint and citrus, have also been shown to affect exercise. Frontiers in Physiology
Heart Attack Risk 31% Lower for People with Strong Chest, Back Muscles: People with stronger back and chest muscles may have a lower risk of heart attack, according to a new study that used artificial intelligence (AI) to analyze heart scans. The study, published in Radiology on June 30, suggests that people with greater muscle density in their chest and back were less likely to have a heart attack and also less likely to die within a decade of a heart scan. “We think that [this] shows that the person has healthier muscles overall and is more likely to take part in exercise. This is evidence to support exercise being good for the heart.”
Sitting Too Much Raises Cancer Risk, But Short Bursts of Light Activity May Help: A new study found that prolonged sedentary behaviors can raise the risk of various cancers, including colorectal, pancreatic, and breast cancer. Replacing just 1 hour of prolonged sedentary behavior per day with light physical activity reduced the risk of cancer death by 12%. While the findings don’t establish causality, they can help guide personalized strategies to break up sitting time. PLOS Medicine
Just 2 Hours of Strength Training May Lower Heart Disease Risk in Women: A new study suggests that women who engage in more strength training during midlife and beyond have a lower risk of cardiovascular disease than those who do not. The findings, published on June 17 in JACC show that heart health benefits increased when strength training was paired with aerobic exercise. Women who perform 150 minutes of weekly aerobic exercise and at least 2 hours of weekly strength training have a 45% lower risk of heart attack. Strength training is considered highly beneficial both during and after menopause.
90 to 119 minutes of strength training a week was linked to a 27% lower risk of dying from neurological disease and a 19% lower risk of cardiovascular death: Researchers followed 147,374 people for up to 30 years and found that 90 to 119 minutes of strength training a week — roughly two gym sessions — was linked to a 27% lower risk of dying from neurological disease and a 19% lower risk of cardiovascular death, with no further longevity benefit. British Journal of Sports Medicine paper
Older adults who walk faster may cut their risk of cognitive decline by half: The findings, published in Neurology, suggest that older adults who maintain a faster natural walking pace tend to have healthier brains and are significantly less likely to experience cognitive decline than their slower-walking peers.
PREVENTION: Sleep
Losing Just 78 Minutes of Sleep a Night Over 6 Weeks May Lead to Weight Gain: A new study suggests not getting enough sleep each night may lead to weight gain.
Those who lost an average of 78 minutes of sleep per night gained almost 1 pound over 6 weeks. People who were short on sleep were also found to be more sedentary.
Sleep deprivation can cause weight gain by altering hunger hormones. Getting good quality sleep is an important part of a healthy weight-management strategy. Annals of Internal Medicine
Night owls are at greater risk of poor metabolic health: Whether you are an early bird or a night owl, your sleep patterns can tell a lot about a person’s eating habits and subsequently the potential health risks. “Both Morning-types and Evening-types consumed similar amounts of food or energy across the day, but it was the timing of eating that was crucial.” Evening-types consumed less food between 3am and 9:59am but more food between 8pm and 2:59am, while the opposite was true for Morning-types. Night owls were more likely to consume lower energy and protein intakes in the morning, and ate foods that were high in energy, carbohydrates and fats late at night. This Evening-type eating and sleeping pattern was associated with greater body fat percentage, belly fat, and higher blood sugar and lipids. Frontiers in Nutrition.
Monash study links sleep apnea with poor memory and greater dementia risk burden in midlife: New research has found sleep apnoea is linked to poorer memory and a greater burden of dementia risk. Routine screening for sleep apnoea may support long-term brain health. Improving the management of sleep apnoea, along with its associated vascular risk factors such as obesity and high blood pressure, may support healthy cognitive ageing. Alzheimer’s & Dementia: The Journal of the Alzheimer’s Association
A study found that around the full moon, participants took longer to fall asleep, slept less deeply and produced less evening melatonin: The full moon has been blamed for sleeplessness for centuries, usually with more folklore than evidence behind it. But one laboratory study from the University of Basel made the old claim harder to dismiss outright. In a controlled sleep experiment, participants around the full moon took longer to fall asleep, had less deep sleep and showed lower evening melatonin, even though the moon itself was not visible to them. a 2013 Current Biology paper by Christian Cajochen and colleagues.
PREVENTION: Diet
5 Cups of Coffee Daily May Lower Your Liver Disease, Cancer Risk By 47%: A recent study has shown that drinking coffee may help reduce your risk of liver disease and cancer. The researchers found that the more coffee you drink, the greater the potential protective effects. Using sugars or sweeteners in your coffee can slightly reduce the protective effects. It is still important to limit your intake of sugar, sweeteners, and highly processed coffee creamers. Clinical Gastroenterology and Hepatology,
Intermittent Fasting Aids Weight Loss, With a Surprising Psychological Benefit: A new study found that following an intermittent fasting dietary plan may be more beneficial for people who tend to “yo-yo diet” — those who jump from one diet to another rather than following a lifelong healthy eating plan. The study compared intermittent fasting to traditional calorie counting. The findings showed that people following either diet lost about the same amount of weight. However, those who adhered to fasting protocols experienced psychological and behavioral benefits, feeling they didn’t need to monitor overeating or count calories to lose weight. The study was published on July 16 in Clinical Nutrition.
Ultra-processed foods increase 'bad' fatty acids in blood, large study finds: The study, published in Critical Reviews in Food Science and Nutrition, suggests that not only does excess fat from UPFs enter the blood, but that the foods may also stimulate the body to produce lipids from excess carbohydrates in the diet.
Eating chili peppers may raise the risk of one deadly cancer: A major review found that people who consumed the most chili peppers had a substantially higher risk of esophageal cancer, though the evidence was less clear for stomach and colorectal cancers. Researchers emphasize that the findings show an association, not proof of cause and effect, and that more research is needed to determine whether moderate consumption carries similar risks. Frontiers in Nutrition
Dementia risk may also be reduced through diet::Natural plant compounds known as polyphenols, found in berries, tea, cocoa, coffee, and extra virgin olive oil, may positively influence biological processes linked to Alzheimer’s disease and other disorders characterized by the gradual loss of nerve cells, according to a review by researchers at Semmelweis University. The analysis, published in Nutrients, suggests that these bioactive compounds may contribute to healthy brain aging.
Eating an avocado a day lowers heart disease risk factor for people with obesity: Eating an avocado every day may decrease heart disease risk in adults with obesity, according to a recent study led by researchers in the Penn State Department of Nutritional Sciences and published in the Journal of Clinical Lipidology. The team found that regular avocado consumption was associated with a reduced concentration of low-density lipoprotein (LDL) particles — proteins that transport cholesterol through the body — in the blood by an amount that corresponds to an approximate 4% reduction in heart disease risk.
First randomized controlled trial shows promise of a ketogenic diet in psychotic disorders: Published today in Schizophrenia Bulletin, a first-of-its-kind randomized controlled trial (RCT) from researchers at the University of California, San Francisco (UCSF), and funded in part by the National Institute of Mental Health (NIMH), adds to growing literature on the potential benefit of a ketogenic diet for treating psychotic disorders. The study, which enrolled participants with schizophrenia-spectrum or bipolar-1 disorders, demonstrated rapid metabolic improvements with a ketogenic diet compared to diet-as-usual during an initial one-month RCT open-label phase. Furthermore, those who continued with the optional four-month single-arm ketogenic diet extension saw meaningful gains across metabolic, psychiatric, and cognitive measures.
Study suggests Mediterranean diet is associated with better psychological well-being: Following a Mediterranean diet may provide additional benefits for mental health. A new study has now linked it to greater psychological well-being among people over the age of 50. published in BMJ Open.
Diet quality and dementia risk in older adults with Alzheimer pathology: This cohort study of older adults found that adherence to a dietary pattern with lower inflammatory potential was associated with lower dementia risk among individuals with Alzheimer disease pathology and broader neurobiological risk. These findings reinforce the importance of targeted dietary dementia prevention strategies not only for the general population but also for individuals already at elevated risk. JAMA Network Open
PREVENTION: Vitamins/Supplements
Creatine Supplements May Help Treat Depression, Early Evidence Shows: A large review suggests that creatine could be an adjunct treatment for major depressive disorder (MDD). However, not all studies in the review found the same benefits for treating depression symptoms with creatine. Those with depression who would like to try creatine should continue with existing treatments, using it only as an add-on. Experts note that creatine supplements have an excellent safety profile when taken as directed. Lifestyle choices such as good sleep, exercise, nutrition, and stress management can also protect brain health. Their findings, however, are mixed, highlighting the need for further large-scale studies. The results were published in Brain Medicine on June 30.
Millions take omega-3 fish oil for brain health but a new study found no benefit: Fish oil supplements successfully delivered omega-3s to the brain, but a two-year study found no meaningful benefits for memory, cognition, or Alzheimer’s-related brain changes. The results challenge the idea that fish oil pills can help prevent Alzheimer’s and shift attention toward overall diet and lifestyle instead. eBioMedicine
High-dose IV vitamin C may lower risks of death and sepsis in trauma patients: High doses of intravenous (IV) vitamin C may lower the risks of death and sepsis in trauma patients, as well as shortening hospital stay, suggests a review of the available evidence published online in the journal BMJ Military Health. Although its effects are biologically plausible, especially given its role in aiding tissue repair and recovery, among other things, the quality of the available evidence isn’t currently good enough to recommend the use of vitamin C in trauma patients, say the researchers.
Study challenges a common belief about vitamin D and sunlight: A study of nearly 300 people across northern Britain found that vitamin D levels often stay low all year in groups most at risk. Surprisingly, summer sunshine did not significantly boost vitamin D levels among older adults or people from minoritized ethnic backgrounds. European Journal of Clinical Nutrition
PREVENTION: Other
COVID Vaccine Study Previously Blocked By CDC Is Out — Here's What It Found: The study, originally slated for publication in an edition of the CDC’s Morbidity and Mortality Weekly Report (MMWR), concluded that COVID-19 vaccines reduced the likelihood of COVID-19-related hospitalization and severe illness among adults by about half. The research was published on June 23 in JAMA Network OpenTrusted Source. The study’s publication arrives months after the Washington Post first reported that it had been blocked in April. Acting CDC Director Jay Bhattacharya questioned the study’s methodology after it had already completed scientific review and received editorial approval.
Want to Slow Your Aging? Multivitamins, Diet, and Fitness May Help: Diet, lifestyle factors, and physical activity levels may help you live longer. Research suggests that a higher level of midlife cardiorespiratory fitness may help you live longer. Frequent aerobic exercise may also slow down the onset of numerous health conditions, such as heart disease, diabetes, and stroke. Another recent studyTrusted Source found that daily multivitamins may help slow biological aging, the deterioration of the body at the cellular level. This compares with the body’s chronological age, the time that has passed since birth. Additionally, an article published in Aging CellTrusted Source in April suggested that some short-term dietary changes may affect biological aging. Focusing on a diet rich in plant-based foods may be particularly beneficial.
Almost Half of Dementia Cases Could Be Prevented: 14 Factors That Can Increase Your Risk: A new study published on June 30, 2026, in The Lancet Healthy LongevityTrusted Source, suggests that there is a gap between people knowing how to prevent dementia and actually putting those principles into practice. Nearly half of dementia cases may be due to 14 risk factors, which people can often address with lifestyle changes. They include: early life low education; midlife hearing loss; high LDL cholesterol; depression; traumatic brain injury; hypertension; physical inactivity; diabetes; smoking; obesity; excessive alcohol consumption; later-life social isolation; untreated vision loss and exposure to air pollution.
Medicare to Cover New Osteoporosis Diagnostic Screening Test: Starting October 5, 2026, BCT will be fully covered as a Bone Mass Measurement (CPT codes 055T-0558T) preventive services benefit for osteoporosis diagnostic screening for eligible Medicare beneficiaries, with retroactive coverage effective to January 1, 2024.
High Levels of Light Exposure Linked to Lower Dementia Risk: High levels of daytime light exposure are associated with a lower risk for dementia, according to a study published online June 24 in General Psychiatry.
TREATMENT
Most Weight-Loss Drugs Do Not Improve Quality of Life or Heart Health: A comprehensive new study has evaluated the effectiveness and safety of medications designed to aid weight loss for adults who are living with overweight or obesity. The analysis, published on July 8, 2026, in The BMJTrusted Source, sheds light on which drugs produce the greatest weight loss, their potential side effects, and their impact on health outcomes such as heart disease and quality of life. This information aims to help patients, doctors, and policymakers make informed decisions about obesity treatments. The study also highlighted that greater weight loss often came with increased side effects, such as nausea, diarrhea, and fatigue, which sometimes led to patients stopping their medication. Drugs like orforglipron and naltrexone-bupropion had the highest rates of discontinuation due to adverse events. Another important finding was the loss of lean mass, particularly with tirzepatide and subcutaneous semaglutide. While these drugs reduced fat mass effectively, they also caused an average lean mass loss of 6% to 8%, which could affect muscle strength and overall health, especially in older adults. In terms of serious health outcomes, subcutaneous semaglutide was the only drug linked with lower risks of death from any cause and heart attacks. Both subcutaneous semaglutide and tirzepatide reduced the risk of heart failure, with tirzepatide also lowering hospital admissions for heart failure. No drug convincingly reduced the risk of kidney failure. Despite these health benefits and weight loss, none of the drugs showed meaningful improvements in quality of life scores after one year, suggesting that weight loss alone may not translate to better overall well-being in the short term.
Twice-Monthly GLP-1 Shot Helps Manage Blood Sugar, Weight Loss in Trial: A new GLP-1 medication demonstrated efficacy in reducing blood sugar in people with type 2 diabetes in a phase 2b clinical trial. Bofanglutide is a biweekly (once every 2 weeks) injection compared to once-weekly shots like Ozempic and Wegovy. The new biweekly GLP-1 also led to weight loss and improvement in cardiometabolic risk factors. Healthline
GLP-1s Like Ozempic, Mounjaro Linked to Reduced Stroke, Heart Risks: Recent research published in BMJ Medicine suggests that GLP-1 medications may support heart health, with cardiovascular benefits increasing with longer duration of use. However, stopping the medication may reduce heart-protective benefits.
Can GLP-1 Drugs Like Ozempic Really Change Your Sense of Smell and Taste? GLP-1 medications prescribed to treat type 2 diabetes may affect a person’s sense of smell and taste, according to a new study. Researchers report that study participants who used GLP-1 drugs had a higher rate of disturbances in taste and smell than people who were only prescribed diabetes medications. They said the effects of GLP-1s on these sensory functions could be connected to the drugs’ absorption into a person’s nervous system. JAMA Otolaryngology – Head & Neck SurgeryTrusted Source.
GLP-1s for $50 a Month? 14 Million Medicare Recipients May Be Eligible: The Department of Health and Human Services (HHS) recently announced the formation of the Medicare GLP-1 Bridge pilot program, which begins on July 1 and lasts until December 31, 2027. Under the pilot project, people enrolled in Medicare Part D who have been prescribed certain GLP-1 medications will be able to purchase those drugs for $50 per month.
Why GLP-1 Drugs May Raise Muscle Loss, Frailty Risk for People Over 65: A new report states that older adults using GLP-1 drugs may have a higher risk of loss of muscle mass, malnutrition, and dehydration. However, the benefits of taking these drugs should be weighed against these risks when the medications are prescribed. The researchers say that GLP-1 drugs benefit older adults by promoting weight loss, lowering blood sugar levels, and improving heart health. Healthline
Zepbound vs. Wegovy: Which GLP-1 Drug Is Best for Weight Loss? A meta-analysis found that one type of GLP-1 medication may be more effective than others. The analysis showed that GLP-1s containing tirzepatide (Zepbound, Mounjaro) helped people lose more weight than those containing semaglutide (Ozempic, Wegovy). Liraglutide (Saxenda) had the lowest weight loss percentage among users. The success of tirzepatide may be due to its dual mechanism, which targets multiple receptors. University of Georgia College of Pharmacy press release.
GLP-1 Drugs Like Wegovy, Mounjaro May Help With Binge Eating Disorder: A new study found that GLP-1RAs could reduce key symptoms of binge eating disorder. These included binge eating severity, loss of control eating, and emotional eating. Experts say that GLP-1RAs could potentially augment existing BED treatments like psychotherapy. eClinical Medicine,
Popular weight-loss drugs Ozempic and Wegovy may slow biological aging: Researchers found that semaglutide, the active ingredient in Ozempic and Wegovy, slowed biological aging markers in adults with HIV, marking the first clinical evidence that the drug may influence human aging. Although the findings are encouraging, scientists say larger studies are needed before concluding that the medication can help people age more slowly. By calming inflammation and reducing excess fat, semaglutide may postpone several molecular signs of aging, pointing to the potential of GLP‑1 receptor agonists to help prevent age‑related diseases. Science Daily
The Newest Frontier for GLP-1s: Clearing Skin Disease: GLP-1s may clear psoriasis rapidly; plaques improved within 2 days in some patients. Benefit may be direct anti-inflammatory skin effect, not solely weight loss. Genetic ↑ GLP-1 receptor activity linked to lower psoriasis/psoriatic arthritis risk. Early data suggest benefit in HS, atopic dermatitis, and wound healing. Future trials needed for GLP-1 monotherapy in skin disease, especially psoriasis. Medscape
Two Studies Link GLP-1 Use to Lower Breast Cancer Risk: GLP-1 receptor agonists (GLP-1 RAs) are associated with reduced incidence of breast cancer among women with overweight or obesity, according to two observational studies. One found that GLP-1 RA users had a roughly 30% lower incidence of breast cancer than was seen in matched nonusers. The smaller of the two, which followed more than 80,000 women at high risk for breast cancer, found a more modest 16% reduction. Using GLP-1 drugs to prevent cancer is “an exciting new frontier that will likely revolutionize the field of oncology, but like any new exciting therapy we need [randomized] clinical trials to understand how to optimally” use them. The larger study was presented as an oral abstract at the 2026 ASCO Annual Meeting. The other study was presented as a poster at the same meeting.
Statins Rarely Cause Severe Muscle Problems, Researchers Say: The risk of serious muscle issues for people who take statins is extremely low, according to a large study. Researchers said less than 1% of people who took the commonly prescribed cholesterol-lowering medication in a study had a 10-year risk of statin-related serious muscular disorders higher than 10%. The results of the study were published on June 25 in The Lancet Digital HealthTrusted Source. The findings follow a February studyTrusted Source that concluded that the risks of serious side effects from statins are low.
McMaster researchers uncover possible cause of muscle pain from widely used cholesterol medication: Millions of people rely on statins – a medication used to lower cholesterol and reduce the risk of heart attack and stroke. But for some, the drugs come with an unwelcome trade-off: muscle pain, weakness and exercise intolerance that can make it difficult to continue treatment. Now, researchers at McMaster University have uncovered a biological pathway that may explain why those side-effects occur, opening the door to future therapies that could make statins easier to tolerate while maintaining their life-saving cardiovascular benefits. Published in Science Advances, the study identifies an immune and metabolic mechanism that drives statin-induced muscle damage, challenging longstanding assumptions about how these side-effects develop.
Common blood pressure drug could make cancer therapy far more powerful: Researchers found that the common blood pressure drug telmisartan can significantly improve the performance of the cancer drug olaparib, potentially expanding its benefits beyond patients with BRCA-related tumors. The combination is already being tested in human clinical trials after showing strong immune-boosting and anticancer effects in preclinical studies. Journal for ImmunoTherapy of Cancer
Common constipation drug may help clear depression brain fog: An existing constipation drug may have an unexpected new use: helping clear the "brain fog" that often lingers after depression. In a small clinical trial, people with a history of depression who took the medication prucalopride for about a week performed better on tests of memory, attention, and thinking speed than those who received a placebo. The drug targets a serotonin receptor found in both the gut and the brain, and researchers saw no significant side effects. Psychological Medicine
Depo-Provera, Other Hormonal Contraceptives Linked to Brain Tumors: A new study revealed a link between certain progestogen contraceptives, including Depo-Provera, and a higher risk of meningioma brain tumors. Meningiomas are brain tumors that are typically benign (noncancerous). The overall risk is low, but it may be higher with prolonged use of specific products, such as Depo-Provera, which carries safety warnings from the FDA. The increased risk was found to be temporary and shouldn’t deter most people from using birth control. JAMA Network Open
This spray-on powder can stop life-threatening bleeding in 1 second: A new spray-on powder developed by KAIST can stop life-threatening bleeding in about one second by instantly forming a strong gel over a wound. It works on deep and irregular injuries where conventional hemostatic products often struggle and remains effective even after years of storage in harsh conditions. Originally created for the battlefield, the technology could also transform emergency care in disasters, ambulances, and hospitals. Advanced Functional Materials
OTHER
No Link Between Prenatal Tylenol Use and Autism, ADHD, Multiple Studies Confirm: In September 2025, the Trump administration suggested that taking Tylenol during pregnancy may raise the risk of autism in children. Many experts have spoken out against this statement. Multiple studies published in 2026 confirmed that there is no evidence to show a link between Tylenol during pregnancy and increased risks of autism or ADHD, including a new 20-year study from Hong Kong. A large Danish study also found no link between Tylenol and an increased risk of autism. A gold standard systematic review and meta-analysis found no evidence to support the idea that acetaminophen during pregnancy raises the risk of autism, attention deficit hyperactivity disorder (ADHD), or intellectual disabilities. Healthline
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Explosive Diarrhea Parasite’ Spreading Across 17 States, CDC Warns. How to Reduce Your Risk:The CDC reportedTrusted Source 145 cases of cyclosporiasis and 20 hospitalizations between May 1 and June 16. However, more recently, a large, sudden cluster of cases has emerged in Michigan. The parasite that causes cyclosporiasis generally spreads when you eat food that is already contaminated with feces. It takes 1 to 2 weeksTrusted Source outside of the body for Cyclospora to become infectious after passing in a bowel movement. Because of this, transmission from person to person is unlikely. It is not fully knownTrusted Source how Cyclospora gets into food and water. The best way to prevent the infection is to avoid eating contaminated foods and drinking contaminated water. Practicing safe food handling can help avoid contamination. This includes: Washing your hands with soap and water before and after handling and preparing raw fruits and vegetables. Wash all fruits and vegetables under running water before cutting, cooking, or eating. Scrub firm fruits and vegetables, like melons and cucumbers, with a clean produce brush. Cut away any damaged or bruised areas before preparing and eating. Refrigerate cut, peeled, or cooked fruits and vegetables as soon as possible, but within 2 hours.
Young Adults Are Aging Faster, Which May Be Driving Higher Cancer Rates: Researchers say younger generations appear to be aging faster than previous generations. They say the phenomenon may explain why certain cancers are rising drastically in young adults. The reasons for faster biological aging aren’t clear, but unhealthy diets, sedentary lifestyles, and exposure to carcinogens are likely factors. Nature MedicineTrusted Source
Eye problems after COVID-19 can now be explained: Mild COVID-19 can cause severe and long-lasting eye problems, according to a study from Linköping University, Sweden. The study also explains why it has been difficult for sufferers to get help: the abnormal eye behaviour cannot be detected by standard methods. The researchers have developed a diagnostic model to detect COVID-related eye problems. In their study, the researchers found long-term inflammation and deterioration of several eye functions controlled by the nerves in the brain. Long-term ocular symptoms following COVID-19 linked to immune dysregulation,
Repeated Low-Level Blasts in Military Training Are Linked to Later Anger and Aggression: After the researchers stripped out every confounder they could name, age, combat exposure, traumatic brain injury, the blunt weight of having been to war, low-level blast still nudged the odds of anger upward. “Although the effect was moderate, our findings do suggest that long-term occupational blast exposure is a risk factor for anger, even independently of other military exposures,” Kennedy says.
The Clinical Cost of Sunscreen Misinformation: According to the EWG’s 2026 Guide to Sunscreens, a mere 20% of the 2784 products they reviewed met their own safety and effectiveness criteria — a data point that if believed at face value, would drive any number of well-intentioned individuals to the DIY lifestyle. As dermatologists, our issue isn’t that patients are asking questions. We want them to. The real problem we both face in our respective practices is how the current narrative mixes up hazard, exposure, and actual clinical risk. This confusion pushes patients away from medical advice and toward dangerous homemade alternatives. The EWG is an advocacy organization, not a regulatory body like the FDA. Their sunscreen guide is not a medical consensus document. Their ratings rely on a scoring system they built themselves, not a widely accepted standard used by the FDA and recognized by the American Academy of Dermatology and the American Cancer Society. For both of us, the real question is whether their framework is being misrepresented to the public. Medscape
Cancer disparities researchers say federal funding changes have disrupted their work: Why are some people more likely to get cancer, and to die from it than others? Rural Americans, for instance, are 18% more likely to die from cancer overall, and Black women are 35% more likely to die from breast cancer than white women. That's according to a recent report from the American Association for Cancer Research, or AACR. Cancer disparity researchers study these gaps and how to close them. Their work has contributed to reductions in many disparities. But the AACR report found that federal policy changes have affected about 93% of surveyed researchers in this field.
TrumpRx promised a supermarket for cheaper drugs but delivered a boutique: TrumpRx, launched in February, now boasts 92 deals on brand-name prescription drugs made by pharmaceutical companies that announced highly publicized agreements with the Trump administration. But nearly six months since the website's launch, those deals on TrumpRx represent fewer than 12% of the more than 800 brand-name drugs made by the participating pharmaceutical companies. A wide range of medicines — including treatments for inflammatory conditions, HIV and cancer — aren't offered by TrumpRx, according to an NPR analysis of a database of drugs on the market maintained by the Food and Drug Administration. NPR
Kitchen Sponges: Can They Look Clean but Harbor Pathogens? Kitchen sponges are among the most commonly used cleaning tools in homes, yet they may also be one of the underestimated sources of foodborne pathogens. Researchers at the German Federal Institute for Risk Assessment(BfR) found that Escherichia coli, Salmonella enteritidis, and Staphylococcus aureus can multiply rapidly in kitchen sponges, even when only small numbers of bacteria are initially present. Importantly, unpleasant odors, discoloration, and a slimy surface did not reliably indicate microbial contamination. Many consumers assume that dry sponges are hygienically safe. However, this study challenges this assumption. During the 3-day drying period, the pathogens remained largely viable. Even after the sponge appeared dry, it continued to serve as a stable reservoir for foodborne pathogens. These findings explain why even dry kitchen sponges can continue to spread pathogens. The complex pore structure of the sponge appears to retain microscopic pockets of moisture that protect bacteria from drying. Simultaneously, bacteria embedded deep within the sponge are difficult to remove through routine cleaning or disinfection. The latest BfR study showed that kitchen sponges are far more harmful than other household items. Within a brief period, they can become densely colonized reservoirs of foodborne pathogens. The BfR recommended replacing kitchen sponges regularly and immediately after they come into contact with raw poultry or other foods that may carry high bacterial loads. If immediate replacement is not possible, heating the sponge in water above 70 °C for at least 2 minutes can significantly reduce bacterial contamination.
CDC Warns Of Parasite Outbreak Tied To Taco Bell Lettuce In 5 States: The U.S. Centers for Disease Control and Prevention (CDC) is warning people not to eat shredded iceberg lettuce served at Taco Bell locations in Indiana, Kentucky, Michigan, Ohio and West Virginia. The warning, posted Thursday night, follows an outbreak of cyclosporiasis that has sickened more than 1,644 people who reported eating at the chain's restaurants in those five states, according to the CDC. The lettuce was grown by a single supplier in Mexico, the U.S. Food and Drug Administration (FDA) said. The agency has increased screening of that company's lettuce at the border and warned that other restaurants and stores could be implicated as the investigation continues. Not every Taco Bell in the five states received the affected lettuce. It was supplied by Taylor Farms, two federal officials who were not authorized to speak publicly told The Times. The Salinas, California-based company is one of the country's largest producers of fresh lettuce and vegetables, with roughly $7 billion in annual revenue.
