COVID
Vaccines
Authorized by the FDA: The
Pfizer-BioNTech vaccine gained approval from the FDA on Dec. 11 for those 16
and older, which was followed by the Moderna Vaccine on Dec. 18. President Trump has said vaccines will be free
to all Americans, though some places may charge a fee for administering the
shots. Initial supplies will be limited. Based on the U.K experience, it’s expected
that people with a history of serious
allergic reactions will be warned about the vaccination. The FDA also said the
vaccine might not be as strong in people with compromised immune systems,
including those taking drugs that weaken the immune system. Both vaccines
employ mRNA technology. It will be up to the states how the vaccine will be
distributed thought the Centers for Disease Control (CDC) recommends that
health-care workers and nursing home and other long-term care residents be the
first to receive the vaccine.
CDC Warns
That COVID-19 Vaccine Might Spur Transient Sickness: Experts attending a meeting of an
advisory committee to the U.S. Centers for Disease Control and Prevention
stressed that Americans who receive the vaccine should not be surprised if they
feel under the weather for a few days afterward.
FDA Give
Guidance on Allergy, Pregnancy Concerns for Pfizer Vaccine: The US Food and Drug Administration
(FDA) has clarified its guidance on administration of the Pfizer/BioNTech
COVID-19 vaccine, stating that it is safe for people with any history of allergies,
but not for those who might have a known history of severe allergic
reaction to any component of the vaccine.
Researchers
urge priority vaccination for individuals with diabetes: Researchers have discovered individuals
with type 1 and type 2 diabetes infected with COVID-19 are three times more
likely to have a severe illness or require hospitalization compared with people
without diabetes. Diabetes
Care
Interpol
Warns Fake COVID-19 Vaccines May Pop Up Online: Interpol
released a warning
last week stating that organized crime networks may try to scam people into
buying fraudulent COVID-19 vaccines. The real vaccine won’t be distributed
online, so avoid circumventing the process for what may seem like early access
to the shot.
Johnson
& Johnson Hopes to Offer COVID Vaccine in February: Johnson & Johnson has fully
enrolled 45,000 participants in phase III of its clinical trials for a
coronavirus vaccine and hopes to apply for an emergency use authorization from
the FDA in February. The Johnson & Johnson vaccine differs from the Pfizer
and Moderna vaccines in that it doesn't need to be frozen and only requires one
dose, not two.
New Home
Test approved by the FDA:
The U.S. Food and Drug Administration on Tuesday authorized the first
coronavirus test that people will be able to buy at a local store without a
prescription and use for immediate results at home to find out if they're
positive or negative. The test will cost about $30 and be available by January.
It takes about five minutes to collect the sample and produces results within
20 minutes.
Plasma From
Recovered Patients Shows Little Benefit in Those Hospitalized With COVID-19: The therapy know as convalescent
plasma, which delivers antibodies from COVID-19 survivors to infected people,
did not significantly improve patients' health status or reduce their risk of
dying from the disease any better than a placebo.
Face masks
slow spread of COVID-19; types of masks, length of use matter: "The results suggest that the
consistent use of efficient face masks, such as surgical masks, could lead to
the eradication of the pandemic if at least 70% of the residents use such masks
in public consistently," said author Sanjay Kumar. "Even less
efficient cloth masks could also slow the spread if worn consistently."
Physics of Fluids
One-third of
patients may experience ‘long COVID’:
A study has found that 32% of people who tested positive for SARS-CoV-2 were
still experiencing at least one symptom 6 weeks after their tests. The most
common of these symptoms were fatigue, shortness of breath, and a loss of taste
or smell. The phenomenon
appears to be more common among people who experienced more severe infections. Among
people with milder infections, however, the prevalence of long COVID has been
unclear. Data from the COVID Symptom Study app suggest that 1 in 10 people with
the illness experience symptoms for 3 weeks or more. Annals of Internal Medicine.
For Covid
Long-Haulers, a Little-Known Diagnosis Offers Possible Treatments—and New
Challenges: a little-known syndrome called POTS: A disorder of the autonomic nervous system that
can have a variety of causes, and it existed before Covid. One common trigger
is an infection, such as a virus. Now some doctors believe that the coronavirus
is triggering the disorder in some people, providing an explanation for
debilitating symptoms including dramatically elevated heart rates from small
movements, dizziness and extreme fatigue after even minor physical activity. The
good news, experts say, is there are protocols and treatments for POTS, which
stands for postural orthostatic tachycardia syndrome. They include a guided,
very gradual return to physical activity; compression stockings or abdominal
compression to prevent blood pooling in the lower half of the body; increased
salt and fluid intake if blood pressure is low; and sometimes medications to
regulate blood pressure, heart rate and blood volume. The Wall Street Journal
Long-Haul
COVID-19 May Be a Public Health Crisis After the Pandemic: On Dec. 3 and 4, the National
Institutes of Health sponsored a meeting to discuss the long-term symptoms of
COVID-19. This shed light on the millions of people around the world who’ve
been affected by lingering symptoms from the disease. Healthline
Large US
study confirms COVID-19 complications: Lung, kidney and cardiovascular issues. Canadian Medical Association Journal
(2020). DOI:
10.1503/cmaj.201686
Baricitinib
Combo for COVID-19 Accelerates Recovery: Among people hospitalized with COVID-19, a combination of baricitinib
and remdesivir reduces the median time to recovery compared with remdesivir
plus placebo, according to trial results
published December 11 in the New
England Journal of Medicine.
Men
Worldwide Doing Worse with COVID-19:
Researchers pooled data from government websites and the medical literature on
more than 3.1 million people infected with the new coronavirus in 46 countries.
They found no difference in the proportion of male and female patients who
contracted COVID-19. Men, however, were nearly three times more likely to be
admitted to an intensive care unit and 39% more likely to die from COVID-19.
Nature Communications
Vitamin D
Deficiency in COVID-19 Quadrupled Death Rate: Vitamin D deficiency on admission to hospital was
associated with a 3.7-fold increase in the odds of dying from COVID-19,
according to an observational study looking back at data from the first wave of
the pandemic. published
online November 25 in the American
Journal of Clinical Pathology.
Metformin Use May Reduce Mortality in Women With COVID-19: For women with type 2 diabetes or
obesity who are admitted to the hospital with COVID-19, metformin use is
associated with significantly reduced mortality, according to a study published
online Dec. 3 in The Lancet
Healthy Longevity.
Study hints
that supplements may reduce COVID-19 risk in females: The research found small but
significant decreases in the risk of SARS-CoV-2 infection among females — but
not males — who took multivitamins, vitamin D, omega-3 fatty acids, or
probiotics. MedRxiv.
LED lights
found to kill coronavirus:
Researchers from Tel Aviv University (TAU) have proven that the coronavirus can
be killed efficiently, quickly, and cheaply using ultraviolet (UV)
light-emitting diodes (UV-LEDs). They believe that the UV-LED technology will
soon be available for private and commercial use. ournal of Photochemistry
and Photobiology B: Biology.
COVID-19
Neurologic Fallout Not Limited to the Severely Ill: A review of medical records of 74 adults (mean age, 64
years) who were hospitalized with COVID-19 and evaluated for neurologic
conditions at Boston Medical Center, a safety-net hospital caring primarily for
underserved, low-income, racial and ethnic minority populations. "We found a range of neurologic diagnoses, including
stroke and seizures, among hospitalized patients with COVID-19 and the majority
were not critically ill, suggesting that these complications are not limited
just to those patients who require ICU care or a ventilator," The study was published
online December 9 in Neurology
Clinical Practice.
COVID Ranks
as Leading Cause of Death in the US.
Tocilizumab
Reduces Odds of Ventilation or Death in Mostly Non-White COVID-19 Patients: The interleukin-6 inhibitor tocilizumab
reduced the combined likelihood of mechanical ventilation or death by 44% among
mostly non-white patients hospitalized with COVID-19, according to a new
international randomized test of 389 volunteers. The New England Journal of
Medicine
We are
over-cleaning in response to covid-19:
We don’t have a single documented case of covid-19 transmission from surfaces.
Not one. Covid is spread mainly through the air so there’s no need to
constantly disinfect surfaces. Shared air is the problem, not shared surfaces.
Washington Post
Elevated biomarker for blood vessel damage found in all children with SARS-CoV-2: Researchers have found elevated levels
of a biomarker related to blood vessel damage in children with SARS-CoV-2
infection, even if the children had minimal or no symptoms of COVID-19. They
also found that a high proportion of children with SARS-CoV-2 infection met
clinical and diagnostic criteria for thrombotic microangiopathy (TMA). Blood Advances
PAIN
Improving
pain care through implementation of the Stepped Care Model for Pain Management: A new study published in the Journal
of Pain Research provides evidence that implementation of a Stepped Care
Model for Pain Management (SCM-PM) has the potential to more adequately treat
chronic pain. The SCM-PM calls for an individualized approach to managing pain
in three steps. In Step 1, the clinician identifies and discusses the patient's
pain concerns, and develops a treatment plan focusing on self-management and
primary care-based interventions. Step 2 involves additional resources and
collaborative treatment, including behavioral health assessment and
interventions, medication, and consultations with specialists. Step 3 focuses
on patients with chronic pain requiring significantly more care and involvement
from other members of a pain management team.
Exercise for
low back pain beneficial but no one agrees on why: A new evidence review has found there
is still no consensus between researchers about why exercise works for low back
pain patients - despite decades of studies on the topic. Musculoskeletal Science and Practice
recently
COMPLEMENTARY & ALTERNATIVE MEDICINE
First meta-analysis shows promise for yoga, meditation, mindfulness in concussion: Data from 22 different studies,
including both published and unpublished work, that included a total of 539
study participants, and looked at the impact of the three interventions on
outcome categories -- including mental health, physical health, cognitive
performance, quality of life, and social/occupational performance -- and on
specific health outcomes, like depression, attention, anxiety, and fatigue.
"The main results that we saw were significant reductions in depression
and fatigue, Especially with fatigue, it was a large effect size, which is
impressive in the sense that fatigue is a difficult symptom for patients to
deal with." Applied
Psychology: Health and Well-being
Does CBD
Impair Your Driving Abilities? Experts, Researchers Disagree: In a new studyTrusted Source, researchers say cannabidiol (CBD)
without the intoxicating chemical tetrahydrocannabinol
(THC) doesn’t impair driving. However, the researchers say that THC itself
can produce mild driving impairment that can last up to 4 hours.
FDA ACTION
• Approved
Xofluza for postexposure flu prevention
• Approved
Tagrisso, the first adjuvant therapy for the most common type of lung cancer
• Approved
the Osseoanchored Prostheses for the Rehabilitation of Amputees (OPRA) Implant
System, the first implant system marketed in the U.S. for adults who have
transfemoral—or above-the-knee—amputations and who have or are anticipated to
have rehabilitation problems with, or cannot use, a conventional socket
prosthesis.
• Approved
Orgovyx the first oral hormone therapy for treating advanced prostate cancer
• Warns
consumers to avoid 50 male enhancement and Weight Loss Products Sold Through
Amazon, eBay and Other Retailers Due to Hidden, Potentially Dangerous Drug
Ingredients
• Granted
marketing authorization for an anterior
cruciate ligament (ACL) implant intended to serve as an alternative to ACL
reconstruction to treat ACL tears.
• Approved
Gallium 68 PSMA-11 (Ga 68 PSMA-11) – the first drug for positron emission
tomography (PET) imaging of prostate-specific membrane antigen (PSMA) positive
lesions in men with prostate cancer.
• Approved
Oxlumo (lumasiran) as the first treatment for primary hyperoxaluria type 1
(PH1), a rare genetic disorder
• Expanded
the approved indication for Xofluza (baloxavir marboxil) to include
post-exposure prevention of influenza (flu) for patients 12 years of age and
older after contact with an individual who has the flu.
• Approved
Zokinvy (lonafarnib) capsules to reduce the risk of death due to
Hutchinson-Gilford progeria syndrome and for the treatment of certain
processing-deficient progeroid laminopathies in patients one year of age and
older
PREVENTION: Exercise
Aim to
exceed weekly recommended physical activity level to offset health harms of
prolonged sitting: The
health harms associated with prolonged sitting can be offset by exceeding
weekly recommended physical activity levels, says the World Health Organization
(WHO) in new global guidelines on physical activity and sedentary behaviour,
published in a special dedicated issue of the British Journal of Sports
Medicine. But all physical activity counts and is good for long term health,
say the new guidelines.
Everyday activities enhance personal well-being: Physical activity makes happy and is important to maintain
psychic health. Researchers studied the brain regions which play a central role
in this process. Their findings reveal that even everyday activities, such as
climbing stairs, significantly enhance well-being, in particular of persons
susceptible to psychiatric disorders. Science
Advances
Large study
finds clear association between fitness and mental health: New research from a large study
demonstrates that low cardiorespiratory fitness and muscle strength have a
significant association with worse mental health. BMC Medicine
PREVENTION: Diet/Nutrition
New ‘Green’
Mediterranean Diet May Be Even Healthier for You: According to a new
study published online in the journal Heart, researchers found that people who consumed
higher amounts of plant-based proteins and less red meat and poultry
experienced increased cardiovascular and metabolic benefits.
Following A Mediterranean Diet Helps Lower The Risk Of Diabetes In Women, New Study Finds. The health harms associated with
prolonged sitting can be offset by exceeding weekly recommended physical
activity levels, says the World Health Organization (WHO) in new global
guidelines on physical activity and sedentary behaviour, published in a special
dedicated issue of the British
Journal of Sports Medicine. All physical activity counts and is
good for long term health, say the new guidelines.
Patients with heart rhythm disorder warned against heavy alcohol consumption: Fourteen drinks a week is linked with a
higher risk of health problems including stroke and embolism in patients with
atrial fibrillation, according to research published in EP Europace, a
journal of the European Society of Cardiology (ESC).
New Study Blood Type Diet
A study published in the Journal of the Academy of Nutrition and Dietetics
by researchers with the Physicians Committee for Responsible Medicine—a
nonprofit of 12,000 doctors—debunks the 'blood type diet' by finding that blood
type was not associated with the effects of a plant-based diet on body weight,
body fat, plasma lipid concentrations, or glycemic control. This new study is
based on a randomized control trial whose main findings were published in JAMA
Network Open on Nov. 30. That trial randomly assigned overweight
participants with no history of diabetes to an intervention or control group on a 1:1
ratio for 16 weeks. Participants in the intervention group followed a low-fat,
plant-based diet. The control group made no diet changes. The key finding is
that a plant-based diet ramps up metabolism as measured by an increase in
after-meal calorie burn of 18.7%, on average, for the intervention group over
the control.
Diet
modifications -- including more wine and cheese -- may help reduce cognitive
decline, study suggests:
The foods we eat may have a direct impact on our cognitive acuity in our later
years. This is the key finding of an Iowa State University research study
spotlighted in an article published in the November 2020 issue of the Journal
of Alzheimer's Disease. Key findings included: Cheese, by far, was shown to be
the most protective food against age-related cognitive problems, even late into
life; The daily consumption of alcohol, particularly red wine, was related to
improvements in cognitive function; Weekly consumption of lamb, but not other
red meats, was shown to improve long-term cognitive prowess; and Excessive
consumption of salt is bad, but only individuals already at risk for
Alzheimer's Disease may need to watch their intake to avoid cognitive problems
over time.
Is the sugar
substitute stevia bad for our health?:
New research into the plant-based sweetener stevia indicates that the sugar
substitute may have negative implications for gut health. Molecules.
An avocado a
day keeps your gut microbes happy:
Eating avocado as part of your daily diet can help improve gut health.
Researchers found that people who ate avocado every day as part of a meal had a
greater abundance of gut microbes that break down fiber and produce metabolites
that support gut health. They also had greater microbial diversity compared to
people who did not receive the avocado meals in the study. Journal of Nutrition
PREVENTION:
VITAMINS/SUPPLEMENTS
Dietary
Supplements and Cognitive Function, Dementia, and Alzheimer’s Disease: What the
Science Says: From the
National Center for Complementary and Integrative Health. This issue of the
digest summarizes current information on what the science says about several
dietary supplements that have been studied for cognitive function, dementia,
and Alzheimer’s disease. Although a few trials of natural products for the
prevention of cognitive decline or dementia have shown some modest effects,
direct evidence is lacking. In addition, research on some mind and body
practices such as music therapy and mental imagery, which have shown promise in
treating some symptoms related to dementia, as well as alleviating stress among
caregivers, is ongoing.
Study Finds
Fish Oil May Not Help Your Heart:
A studyTrusted Source,
published in the Journal of the American Medical Associationon November 15,
found that a high dose of omega-3 fatty acids did not reduce people’s chances
of experiencing a major cardiovascular event.
Eating driedfruit linked to better overall diet and health: Encouraging people to eat more dried
fruit — without added sugar — could be an effective way to boost their intake
of vital nutrients, researchers have concluded. Even after adjusting for demographic and
lifestyle factors, the participants who ate significant amounts of dried fruit
tended to have better diets, a lower BMI, a smaller waist circumference, and
lower systolic blood pressure compared with those who did not. Medical News
Today
Higher doses
of vitamin D did not reduce falls in at risk older adults: A randomized trial found that, compared
with a lower dose, higher doses of vitamin D supplementation did not reduce
falls in older persons at high risk for falls. In addition, several analyses
raised safety concerns about vitamin D3 doses of 1000 IU/d or higher. Annals
of Internal Medicine.
PREVENTION
Anxiety
associated with faster Alzheimer's disease onset: Anxiety is associated with an increased
rate of progression from mild cognitive impairment to Alzheimer's disease,
according to a new study. Radiological Society of North America
Testosterone
can prevent type 2 diabetes in men:
The largest investigation of testosterone treatment ever undertaken has shown
that, over and above the effect of a lifestyle program, treatment with
testosterone prevents or reverses newly diagnosed type 2 diabetes in men. The
Lancet Diabetes & Endocrinology
TREATMENT
Drug for rare disorder shows promise for treating herpes viruses: A drug currently prescribed to treat a
rare enzyme deficiency can help cells clear the herpes simplex 1 and herpes
simplex 2 viruses, according to a new study. Science Advances
New
guideline supports behavioral, psychological treatments for insomnia: A new clinical practice guideline
establishing recommendations for the use of behavioral and psychological
treatments for chronic insomnia disorder in adults has been published. The
guideline includes one strong recommendation -- which is one that clinicians
should follow under most circumstances -- for the use of cognitive behavioral
therapy for insomnia. CBT-I combines one or more cognitive therapy strategies
with education about sleep regulation plus behavioral strategies such as
stimulus control instructions and sleep restriction therapy. Treatment
typically involves four to eight sessions. Journal
of Clinical Sleep Medicine
OTHER
Amazon
Pharmacy Boasts Big Discounts for Prescription Meds, but Probably Isn’t the
Best Deal: Amazon
launched Amazon Pharmacy, a delivery service for prescription medications. The service allows customers to purchase
prescription medications with or without insurance. It boasts that Amazon Prime
members can save up to “80 percent off generic and 40 percent off brand name
medications when paying without insurance.”
Experts say
Amazon Pharmacy has the potential to improve drug pricing in the United States,
but it likely won’t be a game-changer since it will work within the same system
as other online pharmacies. Despite its boasting, Amazon Pharmacy pricing
doesn’t really offer much of a discount. Healthline