Saturday, August 21, 2021

Journal Watch August 2021


COVID

3rd Dose for Moderately or Severely Immunocompromised: Anyone who is moderately or severely immunocompromised, and has received the Pfizer or Moderna Covid vaccine, should receive a third dose. Those qualifying for this shot, distribution which begins the latter part of this week in many states, will need to meet one of the following criteria: Receiving active cancer treatment for tumors or cancers of the blood; organ transplant recipient and taking meds to suppress immune system; received a stem cell transplant in the last two years; taking medications to suppress immune function; moderate or severe primary immunodeficiency (such as DiGeorge Syndrome, Wiskott-Aldrich syndrome; advanced or untreated HIV infection; active treatment with high dose corticosteroids. If you are unsure if you qualify, contact your medical provider.

 

The US Dept. of Health and Human Services have rolled out a plan for a third dose of the Modern/Pfizer Vaccines: On Wed., HHS stated, "Based on our latest assessment, the current protection against severe disease, hospitalization, and death could diminish in the months ahead, especially among those who are at higher risk or were vaccinated during the earlier phases of the vaccination rollout.” Pending FDA and CDC's Advisory Committee on Immunization Practices (ACIP), the roll out will begin the week of Sept. 20. The booster should be scheduled 8 months after the second dose. If your second dose was March 22, the third dose should be given around Nov. 22.

 

Why People Being Treated for Cancer Really Need a Second COVID-19 Vaccine Dose: A study released from the Leukemia and Lymphoma Society (LLS) shows that while the vaccines are safe, about 1 in 4 people with blood cancer fail to produce detectable antibodies after vaccination. Meanwhile, another new studyTrusted Source from Israel cancer researchers published in JAMA Oncology shows that people with solid tumor cancer in active treatment had a “pronounced lag” in antibody production after receiving the first Pfizer-BioNTech COVID-19 vaccine. But the rate increased substantially after receiving the second dose

 

Pfizer Vaccine Protection Wanes After 6 Months: Study: The July 28 preprint report of the study, which has not been peer reviewed, suggests a gradual "declining trend in vaccine efficacy" over 6 months after a two-dose regimen of the Pfizer vaccine. The study included more than 45,000 people worldwide. The study found that overall effectiveness fell from 96% to 84%. A third booster dose of the Pfizer vaccine increases neutralizing antibody levels against the Delta variant by more than five times compared to levels after a second dose in people aged 18 to 55 years, new data from Pfizer show. The immune response to the third dose appears even more robust ― more than 11 times higher than the response to second shot ― among people aged 65 to 85 years.

 

Third Pfizer Dose 86% Effective in Over 60s: A third dose of Pfizer/BioNTech's COVID-19 vaccine was found to be 86% effective in people aged over 60, an Israeli healthcare provider reported, citing initial results from a study of thousands of members.

 

Atypical COVID Symptoms Common in Older Adults: New research provides more evidence that older adults with COVID-19 often present with atypical symptoms, including functional decline and altered mental status, and pinpoints demographic and clinical factors associated with atypical presentation. Those most at risk are adults age 75 and older, women, Blacks and non-Hispanics, those with a higher comorbidity index and those who have dementia and/or diabetes, according to the Journal of Gerontology report. 

 

CDC Calls for Masks in Schools, Hard-Hit Areas, Even if Vaccinated: The Centers for Disease Control and Prevention (CDC) once again is recommending that some Americans wear masks indoors. The agency called for masks in K-12 school settings and in areas of the United States experiencing high or substantial SARS-CoV-2 transmission, even for the fully vaccinated. The move reverses a controversial announcement the agency made in May 2021 that fully vaccinated Americans could skip wearing a mask in most settings. The Delta variant as well as new evidence of transmission from breakthrough cases are largely driving these changes. https://www.medscape.com/viewarticle/955488

 

Risks of the Delta Variant for Vaccinated vs. Unvaccinated People: A new CDC reportTrusted Source shows that since July 26, there have been only 6,587 reports of breakthrough infections that resulted in hospitalization or death among 163 million fully vaccinated people — a percentage of 0.01 percent or less.

 

Massachusetts outbreak demonstrates Delta variant's transmissibility: A series of large public events in a Massachusetts town in July 2021 has been linked to 469 new COVID-19 cases. Three-quarters of these cases were in fully vaccinated people. The vast majority of infections were with the Delta variant of the virus.  Fully vaccinated individuals who contracted the virus appeared to be just as infectious as those who had not been fully vaccinated. As a result, the Centers for Disease Control and Prevention (CDC) now recommend wearing masks in indoor public settings in areas with substantial or high transmission. CDCTrusted Source

 

Breakthrough COVID-19 More Likely Months After Vaccination: People who received their second dose of the Pfizer/BioNTech vaccine five or more months ago are more likely to test positive for COVID-19 than people who were fully vaccinated less than five months ago, new data suggest. Researchers at an Israeli HMO studied nearly 34,000 fully vaccinated adults who were tested to see if they had a breakthrough case of COVID-19. Overall, 1.8% tested positive. Among patients older than 60, the odds of a positive test were almost three times higher when at least 146 days had passed since the second dose. Very few patients had required hospitalization. medRxiv 

 

Vaccination May Cut Risk of COVID Reinfection in Half: A new study published today in the CDC's Morbidity and Mortality Weekly Report shows people who have recovered from COVID-19 but haven't been vaccinated have more than double the risk of testing positive for the virus again, compared with someone who was vaccinated after an initial infection. They found that those who were unvaccinated had more than double the risk of being reinfected during the Delta wave. Partial vaccination appeared to have no significant impact on the risk of reinfection Among those who were reinfected, 20% were fully vaccinated, while 34% of those who did not get reinfected were fully vaccinated.

 

Injectable Monoclonal Antibodies Prevent COVID-19 in Trial: A combination of two monoclonal antibodies given as a subcutaneous injection prevented COVID-19 in patients at a high risk of infection due to household exposure, according to results of a randomized, double-blind, placebo-controlled clinical trial published online August 4 in the New England Journal of Medicine.

 

Moderna Says Boosters May be Needed after 6 months: Moderna says neutralizing antibodies generated by its COVID-19 vaccine against three variants of the virus that causes the disease waned substantially 6 months after the second dose. The new data was presented in an earnings call to investors and is based on a small study that hasn't yet been published in medical literature. 

 

Delta Won’t Be the Last Variant: How Will the Coronivirus Evolve New  from the New Yorker

 

World-first COVID vaccine booster randomized clinical trial in transplant patients proves third shot is very effective. New England Journal of Medicine.

 

US Pediatric Hospitals in Peril as Delta Hits Children: Over the course of the pandemic, COVID-19 has been a less serious illness for children than it has been for adults, and that continues to be true. But with the arrival of Delta, the risk for kids is rising, and that's creating a perilous situation for hospitals across the United States that treat them.  Roughly 1800 kids were hospitalized with COVID-19 in the United States last week, a 500% increase in the rate of COVID-19 hospitalizations for children since early July, according to data from the Centers for Disease Control and Prevention.

 

Youngest Kids More Likely to Spread SARS-CoV-2 to Family: Young children are more likely than their older siblings to transmit SARS-CoV-2 in their households, according to an analysis of public health records in Ontario, Canada – a finding that upends the common belief that children play a minimal role in Covid-19 spread. The study by researchers from Public Health Ontario, published online  in JAMA Pediatrics, found that teenagers (14- to 17-year-olds) were more likely than their younger siblings to bring the virus into the household, while infants and toddlers (up to age 3) were about 43% more likely than the older teens to spread it to others in the home.

 

As Vaccines Wane, Immune System Still Has Weapons Against Delta: More recent studies — but not all — show waning effectiveness of the mRNA vaccines to prevent SARS-CoV-2 infection, especially with high levels of the Delta variant going around. At the same time, the vaccines continue to offer robust protection against severe COVID-19 outcomes. Medscape 

 

Tachycardia Syndrome May Be a Distinct Marker for Long COVID: Tachycardia is commonly reported in patients with post-acute COVID-19 syndrome (PACS), also known as long COVID, authors report in a new article. The researchers say tachycardia syndrome should be considered a distinct phenotype. The study was published online August 11 in The American Journal of Medicine.

 

Lambda Variant Shows Vaccine Resistance: The Lambda variant of the coronavirus, first identified in Peru and now spreading in South America, is highly infectious and more resistant to vaccines than the original version of the virus the emerged from Wuhan, China, Japanese researchers have found.  bioRxiv,

 

COVID-19 an Independent Driver for Heart Attack and Stroke: The risk for acute MI and ischemic stroke increased by roughly eightfold and sixfold, respectively, in the first week following onset of COVID-19 when day 0 (exposure day) was included in the analysis. Even when day 0 was excluded (reducing the risk for bias), the risk for acute MI and stroke was increased by roughly threefold. The study was published online July 29 in The Lancet.

 

Here’s How Well COVID-19 Vaccines Work Against the Delta Variant: Data so far suggests efficacy rates of more than 67 percent for the J&J vaccine, 72 to 95 percent for the Moderna vaccine, and 42 to 96 percent for the Pfizer-BioNTech vaccine. Healthline 

 

COVID-19, Alzheimer’sDisease, and Memory Loss: What We Know: Researchers are learning more about how COVID-19 may impact memory.  In one study, 1 in 10 patients have been reporting memory problems after mild cases of COVID-19 that did not require hospitalization, even 8 months after disease. People who have recovered from COVID-19 but presented with cognitive decline are more likely to be in poorer physical health and have low O2 saturation in their blood. COVID-19 may heighten the risk of developing Alzheimer’s, and COVID-19 can cause an increase in blood-based molecular biomarkers for Alzheimer’s disease. Healthline 

 

No significant benefit of convalescent plasma for COVID-19 outpatients with early symptoms, study shows The final results of the Clinical Trial of COVID-19 Convalescent Plasma in Outpatients (C3PO) demonstrate that COVID-19 convalescent plasma did not prevent disease progression in a high-risk group of outpatients with COVID-19, when administered within the first week of their symptoms. The trial was stopped in February 2021 due to lack of efficacy based on a planned interim analysis. NEJM 

 

Long-HaulCOVID-19 May Affect Two of Three With Mild, Moderate Disease: The majority of individuals who experience mild or moderate COVID-19 infection have persistent symptoms more than 30 days after diagnosis, according to a study published online Aug. 4 in PLOS ONE. The researchers found that the prevalence of PASC at 30 days postinfection was 68.7 percent. The median number of symptoms was three, with the most commonly reported symptoms including fatigue (37.5 percent), shortness of breath (37.5 percent), brain fog (30.8 percent), and stress/anxiety (30.8 percent). Among a subset of 157 participants with follow-up ≥60 days, PASC prevalence was 77.1 percent.

 

 


PAIN        

'Where does it hurt?' predicts chronic pain outcomes, study shows: Pain distribution as reported on a body map, on its own, can be used to assign patients to distinct subgroups that are associated with differences in pain intensity, pain quality, pain impact and clinically-relevant three-month outcomes, according to a new study. PLOS ONE


 Reducing opioids for pain patients linked to higher rates of overdose and mental health crisis: A new study found a 68% increase in overdose events and a doubling of mental health crises among patients who were on stable opioid therapy but had their doses tapered.  JAMA 

 

Widespread pain linked to heightened dementia and stroke risk: Widespread pain is linked to a heightened risk of all types of dementia, including Alzheimer’s disease, and stroke, finds research published online in the journal Regional Anesthesia & Pain Medicine. And this association is independent of potentially influential factors, such as age, general health, and lifestyle, the findings indicate.

 

Study confirms safety of stem cell therapy for chronic knee pain

A study released in STEM CELLS Translational Medicine has confirmed the safety of a novel type of cellular therapy for knee pain caused by osteoarthritis.

 

New app helps relieve back pain: Researchers tested new app called selfBACK.

using a randomized controlled trial that included 461 patients with back pain from Norway and Denmark — and it works. JAMA Internal Medicine

 

Chronic pain might impact how the brain processes emotions: A new study shows that people with chronic pain have an imbalance of neurotransmitters in the part of the brain responsible for regulating emotions. This imbalance could be making it harder for them to keep negative emotions in check – and the researchers think persistent pain might be triggering the chemical disruption.The findings were  published  in the European Journal of Pain.

 


COMPLEMENTARY & ALTERNATIVE MEDICINE

Alternative medicine is widespread among people with MS: A new survey of more than 1,000 people with multiple sclerosis finds that an overwhelming majority use complementary and alternative medicine, with many using cannabis. 81% used dietary supplements such as vitamins, minerals and herbs, up from 65% in the same survey conducted almost two decades ago. 39% used mind-body therapies such as mindfulness and massage, up from 14% in the earlier survey.  81% used exercise to help manage their symptoms - an increase from 67% in 2001. Multiple Sclerosis and Related Disorders.

 

Second-hand marijuana smoke exposure associated with respiratory infections in children: Children whose parents regularly smoke or vape marijuana may experience viral respiratory infections, such as the common cold, more frequently than those whose parents do not smoke, according to a new study.  Pediatric Research

 

Having a good listener improves your brain health: Researchers find having someone to listen to you when you need to talk is associated with greater cognitive resilience. New study shows social interaction in adulthood can stave off cognitive decline despite brain aging. JAMA Network Open

 

Acupuncture improves symptoms of chronic prostatitis/chronic pelvic pain syndrome compared to sham treatment : A multicenter randomized trial showed that 20 sessions of acupuncture over 8 weeks resulted in greater improvement in symptoms of moderate to severe chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) compared with sham therapy. Treatment effects endured over 24 weeks follow up. The findings are published in Annals of Internal Medicine 

 


FDA ACTION

• Approved new indication for Xywav for idiopathic hypersomnia (IH) in adults

• Approved Nexviazyme (avalglucosidase alfa-ngpt) for intravenous infusion to treat patients 1 year of age and older with late-onset Pompe disease.

• Approved Semglee, the first interchangeable biosimilar insulin product, indicated to improve glycemic control in adults and pediatric patients with Type 1 diabetes mellitus and in adults with Type 2 diabetes mellitus.

 

 


PREVENTION: Exercise

Want to Increase Your Physical Activity? Fitness Trackers May Be the Best Way: Researchers say people living with diabetes, heart disease, and obesity can increase their physical activity levels by using fitness trackers. Trackers can provide accountability and help people at all levels motivate themselves. Researchers advise that trackers can provide accountability and help people at all levels motivate themselves. Findings are from an analysisTrusted Source published in JAMA Network Open.

 

Sleep apnea: Exercise and cutting TV time reduce risk: Obstructive sleep apnea (OSA) is a sleep disorder that affects 10–20% of the adult population in the United States. OSA is associated with an increased risk of certain chronic diseases. A new study concludes that being more active and spending less time watching television are linked to a lower risk of developing OSA. European Respiratory JournalTrusted Source.

 

Combination of muscle strengthening and aerobic exercises can reduce cancer mortality: Regular muscle strengthening exercises associated with aerobic activities can reduce cancer mortality, according to a systematic review of epidemiological studies. Workouts with squats, rowing, planks, weight training and so on can reduce the probability of dying from cancer by 14%. When these exercises are combined with aerobic activities, the benefit is even greater, potentially reducing mortality by 28%. International Journal of Behavioral Nutrition and Physical Activity

 

People with stroke who walk 30 minutes per day may have 54% lower risk of death : A new study shows that people who walk or garden at least three to four hours per week, or bike at least two to three hours per week, or the equivalent after having a stroke may have a 54% lower risk of death from any cause. he study found the most benefit for younger stroke survivors. When people under the age of 75 exercised at least that amount, their risk of death was reduced by 80%. Neurology

 

Cancer patients discharged from hospital sooner following preparation for surgery: The approach termed “prehabilitation” includes exercise, nutrition and psychological and social interventions to optimise both physical and mental health before surgery. Researchers found that prehabilitation interventions of between one and four weeks reduced cancer patients’ stay in hospital by 1.8 days compared with standard care. Annals of Surgery

 

Physical activity associated with better cognition in breast cancer patients: Moderate to vigorous exercise may be important in addressing ‘chemo brain’ 

 

Regular exercise, even in polluted areas, can lower risk of death: Regular exercise, even performed in areas with air pollution, can reduce the risk of death from natural causes, according to new research in CMAJ (Canadian Medical Association Journal

 


PREVENTION: Vitamins/Supplements

Growing evidence of vitamin K benefits for heart health: New research has found that people who eat a diet rich in vitamin K have up to a 34 percent lower risk of atherosclerosis-related cardiovascular disease (conditions affecting the heart or blood vessels). Vitamin K1 comes primarily from green leafy vegetables and vegetable oils while vitamin K2 is found in meat, eggs and fermented foods such as cheese. Journal of the American Heart Association

 

Vitamin D may protect against young-onset colorectal cancer: Consuming higher amounts of Vitamin D -- mainly from dietary sources -- may help protect against developing young-onset colorectal cancer or precancerous colon polyps, according to the first study to show such an association. Gastroenterology 

 

Vitamin D reduces the need for opioids in palliative cancer: Patients with vitamin D deficiency who received vitamin D supplements had a reduced need for pain relief and lower levels of fatigue in palliative cancer treatment, a randomized and placebo-controlled study shows. Cancers 

 

Vitamin D supplements ineffective treatment for painful IBS symptoms: New research from University of Sheffield reveals vitamin D supplementation does not improve painful IBS symptoms. Scientists nonetheless noted a high prevalence of poor vitamin D status in people with IBS, so the authors still recommend testing and remedy to support overall health. The definitive study is the largest to provide evidence on effect of vitamin D on IBS symptoms. European Journal of Nutrition

 


PREVENTION: Diet/Nutrition

Iron Deficiency Increasing in U.S. Diets: A new studyTrusted Source published in the Journal of Nutrition reports an increase in iron deficiency in the US. The main reason is high crop yields per acre that are reducing the amount of iron in foods that people and animals eat. Nutritionists recommend people eat more foods with higher iron levels, and foods that help the body absorb iron.

 

Cutting Out 200 Calories a Day and Exercising Can Help You Stay Heart Healthy: A new study has found that older adults with obesity who combined aerobic exercise with a moderate reduction in calories had greater improvements in cardiovascular health than adults who opted for exercise only, or exercise with a more restrictive diet. Circulation

 

Diabetes: Do low glycemic index diets work? A recent analysis, which appears in BMJTrusted Source, suggests that eating a diet of low GI foods may help people with diabetes, particularly type 2, maintain better average blood sugar levels and improve other health parameters.

 

More evidence that a plant-based diet protects heart health: Two recent observational studies looked at the cardiovascular health of people who incorporated more plant-based foods into their diets. One study followed participants for 32 years and found that people with more plant-based diets had lower rates of heart disease. Journal of the American Heart Association. The other study focused on women’s health and learned that women in the postmenopausal stage of life with more plant-centered diets also had a reduced risk of heart issues. Journal of the American Heart Association

 

Moderate drinking may be safe for people with cardiovascular disease: A new study finds that moderate consumption of alcohol may reduce the risk of recurring cardiovascular events. It says people with cardiovascular disease who drink may experience a reduced risk of heart attack, stroke, angina, or death from cardiovascular causes if they consume 7–8 alcoholic drinks per week. People who consumed 6 ounces (oz) of alcohol per day lowered their risk by 50% compared to people with CVD who do not drink. BMC Medicine,

 

The Sick-Quitter Effect: How Alcohol Can Seem Cardioprotective When it Isn’t.: Ever since 60 Minutes ran their story on the French Paradox, people are fixated on the idea that red wine can lower your risk of having a heart attack even if everything else in your life is going wrong. You can smoke and eat unhealthy food, but somehow red wine will fix all that. It won't, of course, and for one very simple reason: The French Paradox, like most medical paradoxes, is a statistical anomaly and is most certainly not true. Medscape

 

New-AF Risk May Not Rise With Light Drinking, May Fall With Wine: A large cohort study saw a familiar J-shaped curve detailing risk for new atrial fibrillation (AF), in which the risk rose steadily with greater number of drinks per week, except at the lowest levels of alcohol intake. There, the curve turned the other way. Light drinkers overall showed no higher AF risk than nondrinkers, and the risk was lowest at any degree of alcohol intake up to 56 g per week. On closer analysis of risk patterns, the type of alcoholic beverage mattered. Modest weekly intake of red wine, at least one serving but no more than seven, may have actually protected against new AF compared with zero intake. published July 27 in JACC: Clinical Electrophysiology.

 

Switching from Western diet to a balanced diet may reduce skin, joint inflammation: Diet rich in sugar and fat leads to disruption in the gut's microbial culture and contributes to inflammatory skin diseases such as psoriasis. Research shows that switching to a more balanced diet restores the gut's health and suppresses inflammation. Journal of Investigative Dermatology

 


PREVENTION

Second-hand marijuana smoke exposure associated with respiratory infections in children: Children whose parents regularly smoke or vape marijuana may experience viral respiratory infections, such as the common cold, more frequently than those whose parents do not smoke, according to a new study. Pediatric Research

 

Lyme disease heightens risk of mental disorders, suicidality: A new study reports that patients hospitalized with Lyme disease had a 28 percent higher rate of mental disorders and were twice as likely to attempt suicide. Physicians and patients should be aware of the potential for psychiatric symptoms post-Lyme infection, particularly during the first year after diagnosis. American Journal of Psychiatry

 

High BMI causes depression – and both physical and social factors play a role: A largescale new study provides further evidence that being overweight causes depression and lowers wellbeing and indicates both social and physical factors may play a role in the effect. With one in four adults estimated to be obese in the UK, and growing numbers of children affected, obesity is a global health challenge. While the dangers of being obese on physical health is well known, researchers are now discovering that being overweight can also have a significant impact on mental health. Human Molecular Genetics 


Examining correlation between occupational noise, heart disease: Hearing conservation programs and policies aim to protect workers from noise-induced hearing loss, but it remains unclear whether stress reactions caused by noise exposure might also lead to other negative health outcomes. Researchers now describe how data from the Canadian Health Measures Survey do not support an association between loud noise exposure and changes in biomarkers for cardiovascular disease or outcomes. The Journal of the Acoustical Society of America

 


TREATMENT

Two types of blood pressure meds prevent heart events equally, but side effects differ: In an analysis of almost 3 million patients taking a single high blood pressure medication for the first time, angiotensin receptor blockers (ARBs) were as good as angiotensin-converting enzyme (ACE) inhibitors at preventing cardiovascular events linked to hypertension, including heart attack, stroke and heart failure. 51 possible side effects and safety concerns were examined: The patients taking ARBs were found to be significantly less likely to develop tissue swelling, cough, pancreas inflammation and bleeding in the digestive tract. Hypertension

 

No more finger pricks: A continuous glucose monitor benefits patients with diabetes in more ways than one: A 15-center study of 175 patients with poorly controlled type 2 diabetes found that continuous glucose monitoring, compared to blood glucose meter monitoring, or finger pricking, significantly decreased their hemoglobin A1C over eight months. JAMA

Switching drugs may not help with antibiotic resistance: In a new study, researchers have shown that antibiotic cycling — which involves doctors switching between antibiotics to overcome antibiotic resistance — may be an ineffective and unsustainable strategy. However, in their study, which appears in The Lancet Microbe, the researchers did find that some subpopulations of bacteria may be appropriate for antibiotic cycling, in limited cases.

Diabetes drugs reduce the risk of Alzheimer’s: People taking certain drugs to lower blood sugar for type 2 diabetes had less amyloid in the brain, a biomarker of Alzheimer’s disease, when compared to both people with type 2 diabetes not taking the drugs and people without diabetes. People taking these drugs, called dipeptidyl peptidase-4 inhibitors, showed slower cognitive decline than people in the other two groups. Neurology 

 

Common weight-loss drug successfully targets fat that can endanger heart health: Researchers have announced successful results of a clinical trial for a commonly prescribed weight-loss drug called liraglutide. In adults who are overweight or have obesity combined with high cardiovascular risk, once-daily liraglutide combined with lifestyle interventions significantly lowered two types of fat that have been associated with risk to heart health: visceral fat and ectopic fat. The Lancet Diabetes & Endocrinology

 

Patients report long-term favorable effects of weight loss surgery in their daily lives: A new study shows that over the course of five years, patients who had bariatric and metabolic surgery to treat uncontrolled type 2 diabetes reported greater physical health, more energy, less body pain, and less negative effects of diabetes in their daily lives, compared with patients who had medical therapy alone for their diabetes. Annals of Surgery

 

Sequential-combinatorial regimens can make treatment more effective for people with aggressive cancers: A new preclinical study suggests that treating people who have aggressive cancers, including melanoma, pancreatic and colorectal cancers, with immune checkpoint inhibitors, quickly followed with mutation-targeted therapy, can help overcome treatment resistance and help people live longer.  Cancer Cell

 

OTHER

When Does Your Metabolism Significantly Decline? It’s Later Than You Think: Many of us think of metabolism as peaking during teenage years when people can “eat anything” without gaining weight and then seeing a slowdown in the metabolic system in midlife in the 30s and 40s as it becomes difficult to keep weight off.  But now, new research finds these long-held ideas about metabolism and age might be incorrect. But research from Duke University has found new information about when this process actually starts and when we can actually blame age for an expanding waistline. Metabolism rates don’t significantly decline until a person reaches their late 50s to 60s.

 

Philips CPAP Machines Are Being Recalled, What to Know: Philips Respironics recalled several sleep apnea machines over concerns that people could be inhaling cancer-causing chemicals through a type of foam that’s embedded in the devices.  The foam is used to reduce the sounds and vibrations emitted by the devices. According to Philips, the foam may break down into small particles. These can then be inhaled and lead to short-term and long-term health issues.  The recallTrusted Source, includes BiPAP and CPAP machines

 

 

 

 

 

 

 

 

 

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