Extract from sour sopleaves can prevent the symptoms of fibromyalgia: The consumption of extract
of Annona muricata L. leaves in pharmaceutical form and in the correct dosage
can reduce the chronic pain, anxiety and depression that accompany this
disease. Journal of Ethnopharmacology
Functional Nasal Surgery Can Improve Headache Symptoms: For appropriately selected patients,
functional nasal surgery is viable for improving headache symptoms, according
to a review published in the December issue of Plastic and Reconstructive
Surgery.
Joint Mobilization Plus Exercise Beneficial for Knee: Patellar mobilization therapy (PMT) plus exercise has the
potential to reduce pain and improve function and quality of life for patients
with knee osteoarthritis, according to a phase 2 study published Nov. 12 in the
Annals of Family Medicine.
Refractory Back Pain Responds to CT-Guided Pulsed RF: Computed tomography (CT)-guided pulsed
radiofrequency (pRF) is effective for patients with acute or subacute
neuroradicular low back pain that is refractory to usual care, according to a
study presented at the annual meeting of the Radiological Society of North
America.
AI-Based Smartphone App Can Help Cut Cancer Pain Severity: An artificial intelligence
(AI)-based smartphone app, called ePal, can reduce the severity of cancer
patients' reported pain and hospital admissions, according to a study presented
at the annual Palliative and Supportive Care in Oncology Symposium.
Treatments Appear No Better Than Placebo for Tennis Elbow: At best, all treatments provide only
small pain relief for tennis elbow, according to a review published online Oct.
31 in the American Journal of Sports Medicine. Only local corticosteroid
injection improved pain at short-term follow-up; however, it was associated
with pain worse than placebo at long-term follow-up. Laser therapy and local
botulinum toxin injection improved pain at midterm follow-up. Extracorporeal
shock wave therapy provided pain relief at long-term follow-up. Only laser
therapy showed better outcomes for grip strength compared with placebo. All
treatments increased adverse events compared with placebo. After receiving
placebo, most patients experienced pain resolution within four weeks of follow-up.
Smoking Linked to Cognitive Dysfunction in Fibromyalgia: Smoking tobacco is a risk factor for
cognitive dysfunction in patients with fibromyalgia (FM), according to a study
presented at the 17th Annual Pain Medicine Meeting, a meeting of the American
Society of Regional Anesthesia and Pain Medicine.
Recommendations Developed for Psoriatic Arthritis Treatment: Recommendations have been developed for
pharmacologic and nonpharmacologic treatment of psoriatic arthritis (PsA); the
evidence-based guideline was published online Nov. 30 in Arthritis &
Rheumatology.
Early PT Can Reduce Risk, Amount of Long Term Opioid Use: Patients who underwent physical therapy soon after being
diagnosed with pain in the shoulder, neck, low back or knee were approximately
7 to 16 percent less likely to use opioids in the subsequent months, according
to a new study. Science Daily
COMPLEMENTARY & ALTERNATIVE MEDICINE
Hypnotherapy Beats Education for Relief of IBS Symptoms: For patients with irritable bowel
syndrome (IBS), individual and group hypnotherapy are more effective than
educational supportive therapy in relieving symptoms, according to a study
published online Nov. 22 in The Lancet Gastroenterology & Hepatology.
Cannabis-based drug in combination with other anti-spasticity: Drugs may help to relieve
symptoms of motor neuron disease Oral spray containing two compounds derived
from the cannabis plant reduced spasticity compared with placebo in patients
already taking anti-spasticity drugs. The Lancet
FDA ACTION
• Updating the US
system for approving medical devices.
• Lifted advisory on
Romaine Lettuce Check Labels for lettuce that is grown outside of the Central
Coast growing regions of northern and central California
• Will take steps to
limit or ban access to flavored electronic cigarettes, menthol cigarettes and
flavored cigars
• Issued a
warning letter to Zhejiang
Huahai Pharmaceutical Co. Ltd. (ZHP), in Linhai, Taizhou Zhejiang China, the
manufacturer of the active pharmaceutical ingredient (API) found in valsartan
that is the subject of an ongoing FDA investigation into probable cancer-causing
impurities in certain commonly prescribed heart medicines.
• Cleared
an app to help increase retention in outpatient treatment program for
individuals with opioid use disorder
•
Approved first treatment for Lambert-Eaton myasthenic syndrome
• Approved
Xospata (gilteritinib) tablets for the treatment of adult patients who have
relapsed or refractory acute myeloid leukemia (AML) with a FLT3 mutation
•
Approved Truxima (rituximab-abbs) as the first biosimilar to Rituxan
(rituximab) for the treatment of adult patients with CD20-positive, B-cell
non-Hodgkin’s lymphoma (NHL) to be used as a single agent or in combination
with chemotherapy
• Accelerated
approval to Vitrakvi (larotrectinib), a treatment for adult and pediatric
patients whose cancers have a specific genetic feature (biomarker).
• Approved
Daurismo (glasdegib) tablets to be used in combination with low-dose cytarabine
(LDAC), a type of chemotherapy, for the treatment of newly-diagnosed acute
myeloid leukemia (AML) in adults who are 75 years of age or older or who have
other chronic health conditions or diseases (comorbidities) that may preclude
the use of intensive chemotherapy.
• Approved
Gamifant (emapalumab-lzsg) for the treatment of pediatric (newborn and above)
and adult patients with primary hemophagocytic lymphohistiocytosis (HLH) who
have refractory, recurrent or progressive disease or intolerance with
conventional HLH therapy.
• Approved
Aemcolo (rifamycin), an antibacterial drug indicated for the treatment of adult
patients with travelers’ diarrhea caused
PREVENTION
Inflammatory bowel disease linked to prostate cancer: Men with inflamed guts are four to five
times at risk for prostate cancer European Urology
Is being a night owl bad for your health? Night owls may have a higher risk of suffering from
heart disease and type 2 diabetes than early risers. Advances in Nutrition
Patient Education Can Improve Chronic Disease Management: An educational intervention can improve
patients' ability to self-manage their chronic diseases, according to a study
published in the November issue of the Journal of the American Osteopathic
Association.
Less Than One Hour of Resistance Training Weekly Tied to Lower CVD Risk: Less than an hour a week
of resistance exercise (RE) is associated with decreased risks for
cardiovascular disease (CVD)-related events and all-cause mortality,
independent of aerobic exercise. Medicine & Science in Sports &
Exercise. Weekly RE frequencies of one, two, and three times or a total of one
to 59 minutes was associated with approximately a 40 to 70 percent decreased
risk for total CVD events, independent of aerobic exercise, compared with no
RE. For weekly RE of more than four times or ≥60 minutes, there was no further
significant risk reduction.
Limiting Social Media May Improve Psychological Well-Being: Limiting social media use to 30
minutes per day may lead to significant improvement in well-being, according to
a study published in the December issue of the Journal of Social and Clinical
Psychology.
Flu Vaccine Linked to Reduced Risk for Death in Heart Failure: After extensive adjustment for confounders, influenza
vaccination is associated with a reduced risk for all-cause and cardiovascular
death among patients with heart failure, according to a study published online
Dec. 10 in Circulation. Compared with intermittent vaccination, annual
vaccinations, vaccination early in the year (September to October), and a
greater number of vaccinations were correlated with larger reductions in the
risk for death.
Sleep Length, Quality Linked to Risk for Falls, Fractures: Women with less than five, more than
10 hours of sleep, poor sleep quality at increased risk for falls. Journal of
Bone and Mineral Research
AHA Guidelines Stress Healthy Lifestyle for Lowering Cholesterol: A healthy lifestyle for lowering cholesterol should be
emphasized for reducing cardiovascular risk across the life course, according
to a guideline published online Nov. 14 in Circulation to coincide with
the annual meeting of the American Heart Association, held from Nov. 10 to 12
in Chicago.
Performance on exercise test predicts risk of death from cardiovascular disease and cancer:Performance on an exercise test predicts the risk of death from cardiovascular
disease, cancer, and other causes, a new study finds. Good performance on the
test equates to climbing three floors of stairs very fast, or four floors fast,
without stopping. The findings underline the importance of fitness for
longevity. EuroEcho-Imaging 2018
Study takes stand on true health benefits of getting up out of your chair: The study, published
in the journal Medicine & Science in Sports & Exercise, reveals that
the 'benefits' of standing over sitting equate to little more than 9 calories
an hour -- the equivalent of just one stalk of celery. In fact, purely for
weight gain perspective, it would take individuals who opted to stand nearly
the entire day to burn just one cup of coffee.
Physical activity in the evening does not cause sleep problems: Contrary to popular belief,
there is no reason to avoid exercising in the evening, an analysis of the
scientific literature has revealed. Sports Medicine
NUTRITION/SUPPLEMENTS/VITAMINS
Low-Carbohydrate Diets Linked to Increase in Calories Burned: Low dietary carbohydrate
intake is associated with increased energy expenditure during weight-loss
maintenance. The BMJ
New evidence that females might benefit most from a low-salt diet: A low-salt diet may be
more beneficial in lowering blood pressure in females than males, report
scientists who found that while actual salt retention isn't higher in females,
there is still an effect that drives pressure up. Hypertension
New review of scientific studies confirms food cravings can be reduced: Food craving, the
intense desire to eat certain foods, can sabotage efforts to maintain healthy
eating habits and body weight, no matter the time of year. However, an
examination of 28 current peer-reviewed scientific studies largely substantiates
findings that changes in diet, prescription medications, physical activity and
bariatric surgery reduce craving. Current Opinion in Endocrinology &
Diabetes and Obesity
Weight cycling is associated with a higher risk of death: Weight cycling, or the constant
losing and gaining of weight (usually from diet), leads to adverse health
outcomes. By some estimates, 80 percent of people who lose weight will
gradually regain it to end up at the same weight or even heavier than they were
before they went on a diet. The Endocrine Society's Scientific Statement on the
causes of obesity found this was because once an individual loses weight, the
body typically reduces the amount of energy expended at rest, during exercise
and daily activities while increasing hunger. This combination of lower energy
expenditure and hunger creates a "perfect metabolic storm" of conditions
for weight gain. Journal of Clinical Endocrinology & Metabolism.
Intermittent fasting: No advantage over conventional weight loss diets: Intermittent fasting
helps lose weight and promotes health. However, it is not superior to
conventional calorie restriction diets, scientists have found out in the
largest investigation on intermittent fasting to date. The scientists conclude
that there are many paths leading to a healthier weight. Everybody must find a
diet plan that fits them best and then just do it! The
American Journal of Clinical Nutrition
TREATMENT
Blood pressure: Early treatment advised by US guidelines has no survival benefits: When is high
blood pressure dangerous? Medical associations offer widely differing answers.
In the USA, for example, patients are seen as hypertensive much sooner than in
Germany. A team has concluded that treating patients sooner does not reduce the
risk of deadly heart disease. It could even negatively affect their mental
health. European Heart Journal
Low Risk of Side Effects for Statins: Statins are associated with a low risk for side
effects, according to a scientific statement from the American Heart
Association (AHA). he risks for statin-induced serious muscle injury and
serious hepatotoxicity are <0 .1="" 0.001="" 0.2="" a="" about="" and="" between="" cancer="" cataracts="" causal="" cognitive="" convincing="" diabetes="" diagnosed="" dysfunction="" erectile="" evidence="" for="" is="" mellitus="" nbsp="" neuropathy="" newly="" no="" of="" or="" p="" per="" percent="" peripheral="" relationship="" respectively="" risk="" seen="" statin-induced="" statins="" tendonitis.="" the="" treatment.="" was="" year="">
Among older women, the naturally occurring hormone DHEA may
preserve bone and muscle mass when compared with placebo, study suggests. Clinical Endocrinology
OTHER
Fear Impacts Quality of Life for Young Adults With Type 1 Diabetes: Fear of complications and
frustration at the amount of time required to manage type 1 diabetes impact the
quality of life of young adults with the disease, according to a study
published in the December issue of The Diabetes Educator.
Some E-Cigarette Liquids Contain Erectile Dysfunction Meds: Consumers should not use two
electronic cigarette liquids that contain erectile dysfunction drugs because
they may pose health risks, according to the U.S. Food and Drug Administration.
Lab tests revealed both sildenafil and tadalafil in E-Cialis HelloCig E-Liquid
and sildenafil in E-Rimonabant HelloCig E-Liquid. The e-liquids are made by
HelloCig Electronic Technology Co. Ltd., based in Shanghai.
Recalled KotexTampons Can Unravel Inside Body: Certain Kotex tampons are being recalled
by Kimberly-Clark because they can unravel and leave pieces inside women's
bodies. There have been "a small number of reports of infections, vaginal
irritation, localized vaginal injury, and other symptoms" among users of U
by Kotex Sleek Tampons, Regular Absorbency, according to the company, CBS News
reported.
Online Tool Helps Patients with Advance Care Planning: The patient-facing PREPARE advance care planning program
plus an easy-to-read advance directive significantly increases documentation of
advance care planning and patient-reported engagement, according to a study
published online Oct. 29 in JAMA Internal Medicine.
Name-Brand Medications Driving Spike in U.S. Drug Spending: "Total prescription
drug spending increased 10 percent annually since 2010," and 82 percent of
prescriptions were for cheaper, generic drugs, according to the Blue Cross Blue
Shield study, NBC News reported. But the study also showed that expensive
"branded prescription drugs accounted for only 17 percent of total
prescriptions filled, but 79 percent of total prescription drug spending [$79.5
billion]." The biggest costs were from three rheumatoid arthritis drugs --
Humira, Remicade, and Enbrel -- a quick-acting insulin called Novolog, and
Neulasta, an immune system-strengthening treatment for cancer patients, NBC
News reported.
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