Saturday, October 18, 2014

Journal Watch October 2014


CHRONIC PAIN
 Complementary Health Approaches for Chronic Pain: This issue of the NCCAM Clinical Digest summarizes current scientific evidence about the complementary health approaches most often used by people for chronic pain. The scientific evidence to date suggests that some complementary health approaches may provide modest, short-term effects that may help individuals manage the day-to-day variations in their chronic pain symptoms. In most instances, though, the amount of evidence is too small to clearly show whether an approach is useful. 

• Acupunctureand Chronic Knee Pain: Researchers randomly assigned 282 patients with moderate to severe chronic knee pain to one of 4 groups, no acupuncture, needle acupuncture, laser acupuncture or sham laser. Treatments were performed for 12 weeks. There were no significant differences in pain relief or physical function between needle, laser or sham acupuncture either at 12 weeks or 1 year. And while there were modest improvements in pain and function comparing one or both of the active treatments with the control group at 12 weeks, the relief was not maintained at 1 year. JAMA 

COMPLEMENTARY AND ALTERNATIVE MEDICINE
 Jazz and Silence Help Reduce HeartRate After Surgery: Patients who listen to music or experience silence while recovering from surgery might need less pain medication, and may be more relaxed and satisfied, concludes a study of women undergoing elective hysterectomies. Anesthesiology 2014 Annual Meeting 

What20 years of cannabis research has taught us: A major new review sets out the latest information on the effects of cannabis use on mental and physical health. While cannabis does not produce fatal overdoses, long term users have a variety of adverse effects including: dependence syndrome, risks of psychotic disorders; lower educational attainment; doubles the risk of being diagnosed with schizophrenia. Addiction 

• CAM Most Used for Chronic Conditions: Complementary and alternative medicine is most often used for the treatment of chronic skin conditions rather than acute skin conditions, and herbal therapies are the most common form of treatment used. JAMA Dermat. 


 FOOD AND DRUG ADMINISTRATIVE ACTION
• Mars Chocolate North America Issues Allergy Alert Voluntary Recall On Undeclared Peanut Butter In M&M’s® Brand Milk Chocolate Theater Box 

• Approves the first combination tablet (Harvoni) to treat patients with chronic hepatitis C virus (HCV) genotype 1 infection. The tablet contains ledipasvir and sofosbuvir.

• Approved Lumason (sulfur hexafluoride lipid microsphere) for patients whose ultrasound image of the heart (echocardiograms) are hard to see with ultrasound waves. 

• Approved the Lutonix 035 Drug Coated Balloon Percutaneous Transluminal Angioplasty Catheter (Lutonix DCB). This is the first drug-coated balloon used to re-open arteries in the thigh (superficial femoral arteries) and knee (popliteal arteries) when narrowed or blocked as a result of peripheral artery disease (PAD).

• Approved Ofev and Esbriet to treat idiopathic pulmonary fibrosis

PREVENTION
• Healthy Lifestyle Behaviors May Prevent 80% of Heart Attacks: Middle-aged and older men were much less likely to have heart attacks over an average of 11 years if they drank moderately, didn't smoke and did everything right on the diet, exercise and weight fronts. Journal of the American College of Cardiology

Can All Work and No Play Make You Diabetic? People who worked more than 55 hours a week at manual labor or other types of "low socioeconomic status jobs" were 30 percent more likely to develop diabetes than those who worked 35 to 40 hours a week. The Lancet Diabetes & Endocrinology 

Nature Walks With Others May Keep Depression at Bay: Taking nature walks with other people may lower your stress levels and reduce your risk of depression, a new study suggests. Ecopsychology 

• Living Near a Highway May Be Bad for Your Blood Pressure: Among more than 5,000 postmenopausal women, those who lived within 109 yards of a busy road had a 22 percent greater risk of developing high blood pressure than women living at least half a mile away, researchers report. Journal of the American Heart Association 

• HealthyLifestyle May Reduce Stroke in Half for Women: Women with a healthy diet and lifestyle may be less likely to have a stroke by more than half, according to a study published in the online edition of the journal Neurology 

• Healthy Habits Might Reduce Colon Cancer Risks: Researchers examined how five lifestyle factors affected colon cancer risk: healthy weight; low amounts of belly fat; regular physical activity; not smoking and limiting alcohol consumption; and a well-balanced diet. This diet was high in fruits, vegetables, fish, yogurt, nuts and seeds, and foods rich in fiber, and low in red and processed meat.
The more of these factors people had, the lower their risk for colon cancer, according to the researchers. BMC Medicine 

• High Cholesterol Tied to Prostate Cancer’s Return: After surgery for prostate cancer, elevated levels of cholesterol and triglycerides may be linked with greater risk of the cancer's return, a new study suggests. Cancer Epidemiology, Biomarkers & Prevention 

 Is“Slow and Steady” Weight Loss Really the Best Way to Loose Weight?: A new study found that that whether you opt for a "crash" diet or something a bit slower, the rate at which you shed excess pounds has no bearing on whether or not those pounds will come back. The Lancet Diabetes & Endocrinology 10/15/14 

• More Evidence That Exercise May Help Fight Depression: Physically active people are less likely to show signs of depression, a new study finds. And exercise can help improve mood in people who already feel depressed, but there's a catch: Depressive symptoms appear to be a barrier to physical activity, the British researchers said. The findings, based on 11,000 adults ages 23 to 50, correlate with previous research suggesting that exercise can have a powerful effect on depression, although it's far from a cure-all. AMA Psychiatry 

SUPPLEMENTS/NUTRITION/VITAMINS
Which cereals are the healthiest: Consumer Reports has taken out the guess work. Check out their chart for which cereals are the healthiest. 

• Gene Study Finds No Proof Vitamin D Guards Against Type 2 Diabetes: British researchers investigated the association between diabetes risk and vitamin D by focusing on genes that control blood levels of vitamin D. They found no connection between different variants of these genes and the risk of developing type 2 diabetes. The Lancet Diabetes & Endocrinology 

• Fish Oil and Fibrilation: High-dose fish oil does not stop AFib recurrence in patients who aren’t receiving traditional therapy. The researchers say the fish oil failed to reduce inflammation or stress markers, which may explain why it didn’t work. Journal of the American College of Cardiology 

• Mediterranean Diet Can Reverse Metabolic Syndrome: For people with metabolic syndrome, a Mediterranean diet supplemented with extra-virgin olive oil or nuts may help reverse the condition. Canadian Medical Association Journal. 

• If You Do Gain Weight, Polyunsaturated Fats May Prevent Some Damage: Muffins -- and other fatty foods -- can definitely put on the pounds, but those made with polyunsaturated oil may be safer for your heart than if they're made with saturated fats like butter, a small study suggests. That's because olive oil, sunflower oil and other polyunsaturated fats won't increase cholesterol like butter or palm oil, the researchers found. Journal of the American Heart Association 

• Even Decaf Coffee May Help the Liver: Another study suggests that coffee might actually be healthy for your liver, and that even decaffeinated coffee may have this effect. Hepatology 

TREATMENT RESEARCH
• Behavioral Therapy Deemed Best forSocial Phobia: In a review of 101 clinical trials, researchers found that "cognitive behavioral therapy" often helped people with social phobia -- a type of anxiety disorder where people have a deep fear of being judged by others or embarrassed in public. The Lancet Psychiatry 

• Common Painkillers Tied to Blood Clot Risk, StudySuggests People who use painkillers called nonsteroidal anti-inflammatory drugs (NSAIDs) -- which include aspirin, naproxen (Aleve) and ibuprofen (Advil, Motrin) -- may be at increased risk for potentially deadly blood clots, a new study suggests. Rheumatology 

• EvolocumabSignificantly Reduces LDL-C Levels in Patients With FamilialHypercholesterolaemia: Evolocumab is highly effective at reducing low-density lipoprotein cholesterol (LDL-C) levels with few side effects in people with familial hypercholesterolaemia (FH), according to 2 studies published in The Lancet

• Long-ActingInsulin Superior to Intermediate-Acting Form for Patients With Diabetes: Long-acting insulin is safer and more effective than intermediate-acting insulin for patients with type 1 diabetes, according to a study published in BMJ. 

Leading lung health organizations releasefirst-ever evidence-based patient care guidelines in prevention of acuteexacerbations of COPD: The American College of Chest Physicians (CHEST) and the Canadian Thoracic Society (CTS) announced Oct. 16 the release of Prevention of Acute Exacerbation of Chronic Obstructive Pulmonary Disease: American College of Chest Physicians and Canadian Thoracic Society Guideline in the journal CHEST. The guideline, a first of its kind, provides evidence-based recommendations aimed at prevention of COPD exacerbations, which can cause frequent hospital readmissions, death during or after a hospital stay, and can potentially greatly reduce the quality of life for patients along with carrying a heavy financial burden. 

OTHER
The More Wired You are, the Less Dense YourGray Matter: Researchers found that people who often use several forms of media simultaneously had lower gray matter density in a specific area of the brain than those who used just one device occasionally. It's conceivable that individuals with less dense gray matter are more inclined to multitask due to weaker socio-emotional regulation. But it's equally plausible that higher levels of exposure to multitasking situations can lead to structural changes in the brain. PLoS One

It's time to get mad about the outrageous cost of health care: Why it’s so high, how it affects your wallet—and yes, what you can do about it from Consumer Reports. 

5 Physical therapy treatments you probably don't need: The American Physical Therapist Association, in conjunction with Choosing Wisely and Consumer Reports has identified five treatments that you don’t need from a physical therapist and what you can do instead. 

• US Life Expectancy Hits Record High of Nearly 79 Years: Average life expectancy in the United States reached an all-time high of 78.8 years in 2012, federal officials reported Wednesday. The increased life expectancy is likely due to Americans living healthier lifestyles, according to researchers from the U.S. Centers for Disease Control and Prevention. Mortality in the United States, 2012 

• Genes May Make Some More Prone to Heart Disease When Under Stress: Genes may interact with stress to trigger heart disease in some people, a new study suggests. The genetic risk occurs in about 13 percent of people, but only in those who are white. The finding could help these people reduce their heart disease risk through simple measures such as exercise, a healthy diet and stress management, the Duke University researchers said. European Journal of Human Genetics 

•  Chewing Gum While fasting beforeSurgery is Safe: Although chewing gum significantly increases the volume of liquids in the stomach, it is safe to administer sedatives or anesthesia to patients who have chewed gum while fasting before surgery, reports a new study. Anesthesiology 2014 

• Children with ChronicHealth Problems Less Likely to Graduate from High School: Approximately 32 million U.S. children have at least one chronic health condition, which can negatively affect their chances of receiving a high school diploma or its equivalent by age 21, finds a new study in the Journal of Adolescent Health






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