Saturday, August 15, 2015

Journal Watch August 2015

CHRONIC PAIN

Knee Replacement May Ease Pain for Rheumatoid Arthritis: Knee replacement surgery can temporarily return the joint to an earlier, better level of function in patients with rheumatoid arthritis, new research suggests. Arthritis & Rheumatology, online 

• Drinking May Ease Fibromyalgia Pain but be Wary: Moderate to heavy drinking might cut the likelihood of disability for people with chronic widespread pain such as that related to fibromyalgia, new Scottish research suggests. But U.S. pain specialists say consuming alcohol is the wrong approach to coping with disabling pain. Arthritis Care & Research 

 Online Program Helps People with Chronic Pain: People can manage chronic pain and reduce their reliance on opioids through an Internet-based program that teaches non-medical alternatives like increased physical activity, thinking more positively and dealing with emotions, a new report suggests. Pain Management Nursing 

• Most Chronic Pain Patients Use Alternative Therapies but Don’t Tell Doctor: More than half of chronic pain patients in a managed care setting reported using chiropractic care or acupuncture or both, but many of these patients didn't discuss this care with their primary care providers. These study results suggest that better care coordination is needed among patients and physicians. American Journal of Managed Care

COMPLEMENTARY AND ALTERNATIVE MEDICINE
 Mindfulness Therapy Might Help Ease PTSD: Mindfulness Based Stress Reduction (MBSR) seems to help veterans cope with post-traumatic stress disorder (PTSD), a new study suggests. As mindfulness skills increased, patients showed improvement in PTSD symptoms such as nightmares, flashbacks of the traumatic event and avoiding things that might remind them of the traumatic event. In addition, patients experienced improvements in irritability, depression and quality of life. JAMA 

• Regular Pot Use as Teen Not Tied to Long-Term Health Problems: Regular marijuana use doesn't appear to put teens at increased risk for depression, lung cancer or other physical and mental health problems later in life, contends a new study that challenges previous research. Psychology of Addictive Behaviors 

• Tuning into Favorite Music May Boost Post Op Recovery: A review of 72 studies, that includes nearly 7,000 patients, investigators found that listening to music before, during or after surgery significantly lowered patients' anxiety and pain, decreased their need for pain medicines, and increased their satisfaction with their care. The Lancet 

FDA ACTION
• Approved Praluent injection, the first cholesterol lowering treatment approved in a new class of drugs known as propotein convertase subtilisn kexin type 9 inhibitors.
• Wants to strengthen sugar labeling adding ‘percent daily value’
• Approved Odomzo, a pill for locally advanced basal cell carcinoma, the most common form of skin cancer.
• Approved Technivie (ombitasvir, paritaprevir and ritonavir) to be used with ribavirin to treat HCV genotype 4 infection
• Approved Spritam, the first 3-D printed pill, to be taken with other medicines for seizures
• Approved OxyContin for Children as Young as 11

PREVENTION
• Exercise May Buffer Symptoms of Early Alzheimer’s: Regular exercise may be the best medicine for seniors facing the onset of dementia, according to three new clinical trials. Physical activity improved mood, memory and ability to think for participants in all three studies. Alzheimer's Association International Conference

• Moderate Exercise May Reduce Men’sHeart Failure Risk: Researchers found that those who exercised by walking or cycling at least 20 minutes a day had a 21 percent lower risk of heart failure. Exercising more than an hour a week decreased risk by 14 percent, the study found. The least-active group had a 69 percent higher risk for developing heart failure, while the highest-intensity group had a 31 percent higher risk of heart failure, the study revealed. There was no information on whether the high-intensity exercisers did marathons or other similar activities. Journal of the American College of Cardiology: Heart Failure. 

 Older Smokers with Migraines and Stroke Risk: A study of nearly 1,300 people, average age 68, who suffered migraine headaches with and without aura found no association between migraine and the risk of heart or stroke in non smokers. But among smokers, migraine was associated with a threefold increased risk of stroke. Neurology

• Stand, Don’t Sit: A new study found that sitting appears to be linked to increased blood sugar and cholesterol levels, which can lead to added weight, diabetes and heart ills. But standing more helps improve all these measures and can give you a trimmer waist to boot, the researchers said. European Heart Journal 

Standing All Day May Take Toll on Health: Desk jobs aren't good for your health, but working on your feet could spell trouble, too, researchers say. Standing five hours a day contributes to significant and prolonged lower-limb muscle fatigue, a small study concluded. This may raise your risk for long-term back pain and musculoskeletal disorders. Human Factors

 • Targeted Workouts May Strengthen Bone sin Middle Age Men: Certain types of exercise improve bone health in middle-aged men with low bone mass and may lower their risk for osteoporosis, according to a small new study. Only those who did weight-lifting had increases in hip-bone density, the study found. Bone 

• Birth Control Pills May Cut Risk of Uterine Cancer: Taking birth control pills, even for just a few years, offers significant long-term protection against uterine cancer, also known as endometrial cancer, the British researchers said. And the longer a women takes birth control pills, the greater her reduction in risk for the disease. The Lancet Oncology 

SUPPLEMENTATION/VITAMINS/NUTRITION
 Healthy Diet May Help Shield the Aging Brain: Older adults with healthier diets reduced their odds of impaired "executive function" by 35 percent. Executive function refers to a collection of things done by the brain, including memory, reasoning, multi-tasking, problem-solving and planning skills. Alzheimer's Association International Conference 

• High Soda Intake May Boost Diabetes Risk, Even without Obesity: Whether you are slim or obese, if you drink lots of sugary soda or other sweetened drinks you are more likely to develop type 2 diabetes, a new analysis reveals. BMJ online 

Spicing Up Meals May Extend Life: A large multi-year food analysis found that adults who reported eating spicy foods -- such as fresh and dried chili pepper -- as little as three days per week were less likely to die during the study period than those who consumed such foods less than once a week. "If you eat more spicy food, it's better for your health and lowers the risk for mortality, especially as it relates to cancer and heart disease." BMJ 

Yo-Yo Dieting Won’t Raise Cancer Risk: This type of dieting, also called weight cycling, features repeated episodes of weight loss followed by weight gain. Previous research has suggested that weight cycling may trigger biological processes that could lead to cancer. Data from more than 132,000 men and women who were aged 50 to 74 when they enrolled in an American Cancer Society study in 1992 found that yo-yo dieting was not associated with overall cancer risk or increased risk. American Journal of Epidemiology 

• Low Fat May Beat Low Carb Diet for Trimming Body Fat: When it comes to slimming down, a diet low in fat seems to beat a diet low in carbohydrates for body fat loss, new research suggests. The finding stems from a small U.S. National Institutes of Health (NIH) investigation that tracked each approach to weight loss among 19 obese adults. Cell Metabolism 

Diet High in Refined Carbs  Could Increase Depression Risk: High-glycemic-index (GI) diets could increase the risk of depression in postmenopausal women, according to a study published in the August issue of the American Journal of Clinical Nutrition

• Vitamin D Supplements Won’t Strengthen Older Women’s Bones: High doses of vitamin D do not appear to protect postmenopausal women from the dangers of osteoporosis, new research indicates. JAMA Internal Medicine 

• Omega 3-Fatty Acids May Help Improve Treatment, Quality of Life for Cancer Patients: Adding omega-3 fatty acids to anti-tumor medications may improve treatment response and quality of life for cancer patients according to a new study. The study examined 50 patients with advanced pancreatic cancer. American Society for Parenteral and Enteral Nutrition 

• Mixed Results on Testosterone Supplements: Testosterone therapy may not be as bad for men's heart health as previously thought, but it doesn't seem to turn back time on their sex lives either, a new trial shows. JAMA

TREATMENT
• Deep Brain Stimulation for Depression Fails to Demonstrated Efficacy: A large number of relatively small open-label studies have supported the effectiveness of various forms of deep brain stimulation (DBS) for both depression and obsessive-compulsive disorder. In the current issue of Biological Psychiatry researchers report the results of the first large-scale, randomized, placebo-controlled trial of DBS treatment for treatment-resistant symptoms of depression, which failed to find that DBS reduced depression symptoms better than placebo.

• Cell Damage Occurs When People Have CT Scans: Cellular damage occurs when people undergo CT scans, but whether or not this causes cancer or any other health problems is unclear, a new study finds. Journal of the American College of Cardiology: Cardiovascular Imaging 

OTHER
• Dementia Risk May Be Dropping With Generations: New research suggests that people born after 1930 may have a lower risk of developing dementia than the generation before them, adding to evidence that the incidence of dementia may be declining in the United States and elsewhere. That decline was not explained by age, but did seem to be related to improvements in heart health over time, the researchers found. Alzheimer's Association International Conference 

• 1 in 5 US Adults Has a Physical, Mental Disability: More than 50 million Americans live with a disability, health officials reported Thursday. The most common disabilities are mobility limitations, such as having serious difficulty walking or climbing stairs -- affecting one in eight adults -- followed by disabilities in thinking and/or memory, independent living, seeing and self-care, according to a new report from the U.S. Centers for Disease Control and Prevention 


• 1 in 4 Senior Women in US has Osteoporosis: The weakening bones of osteoporosis greatly raise a person's odds for dangerous fractures, and a new report finds that one-quarter of all American women aged 65 or older suffer from the condition. Close to 6 percent of men in this age group also have osteoporosis, according to the report from the U.S. Centers for Disease Control and Prevention. 

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