COVID
New Data on
COVID-19's Cognitive Fallout:
Patients hospitalized with COVID-19 experience cognitive and behavioral
problems post-discharge, new research shows. "We showed that cognitive and
behavioral alterations are associated with COVID-19 infection within 2 months
from hospital discharge and that they partially persist in the post-COVID
phase.” Congress of the European Academy of Neurology (EAN) 2021.
Profound
Brain Changes Found in Patients Who Died of COVID-19: The most comprehensive molecular study
to date of brain tissue from people who died of COVID-19 provides clear
evidence that SARS-CoV-2 causes profound molecular changes in the brain,
despite no molecular trace of the virus in brain tissue. The study was published online
June 21 in Nature.
COVID
Pandemic Fuels a Drop in US Life Expectancy: Average U.S. life expectancy dropped by almost two years
from 2018 to 2020, largely because of the coronavirus pandemic. Minorities
experienced a decline several times that of white Americans, according to a new
study published in The BMJ.
23% of
Patients With COVID Report Long-Haul Symptoms: "Many patients recover from
COVID-19 within a few weeks, but some exhibit persistent or new symptoms more
than four weeks after first being diagnosed," with some displaying
symptoms up to nine months later, a study by the nonprofit FAIR
Health said. A month after diagnosis, about 50% of hospitalized
patients reported symptoms, compared to 27.5% of patients who had symptoms and
weren't hospitalized and 19% who were asymptomatic. The top post-COVID symptoms
were pain, breathing difficulties, hyperlipidemia (high cholesterol), fatigue,
malaise, and hypertension. The most common mental health conditions reported
were anxiety, depression, adjustment disorders and tic disorders. The risk of
death 30 days after COVID diagnosis was 46 times higher for patients who were
hospitalized and discharged than for patients who weren't hospitalized.
Arthritis
Drug Tocilizumab Gets FDA EUA for Severe COVID-19: The US Food and Drug Administration
(FDA) issued an emergency use authorization (EUA) for the arthritis drug
Tocilizumab (Actemra) for adults and children aged 2 years and older who are
hospitalized with severe COVID-19 and are being treated with systemic
corticosteroids and supplemental oxygen, noninvasive or invasive mechanical
ventilation, or extracorporeal membrane oxygenation. The drug is not authorized
for use in outpatients with COVID-19.
FDA Adds
Myocarditis Warning to mRNA COVID-19 Vaccines: The FD) is adding a warning to the fact
sheets for the Pfizer/BioNTech and Moderna mRNA COVID-19 vaccines as
medical experts continue to investigate cases of heart inflammation, which are
rare but are more likely to occur in young men and teen boys. The incidents are
more likely to follow the second dose of the Pfizer or Moderna vaccine, with
chest pain and other symptoms occurring within several days to a week, the
warning will note.
Nearly All
COVID Deaths in US Are Now Among Unvaccinated: An Associated Press analysis of
available government data from May shows that "breakthrough"
infections in fully vaccinated people accounted for fewer than 1,200 of more
than 853,000 COVID-19 hospitalizations. That's about 0.1%. And only about 150
of the more than 18,000 COVID-19 deaths in May were in fully vaccinated people.
That translates to about 0.8%, or five deaths per day on average. Medscape
COVID-19
Vaccines Safe, Effective for Patients With Migraine: It is safe for patients with migraine
to receive any of the COVID-19 vaccines without concern about the vaccination
interfering with their migraine medications or the medications reducing an
immune response to the vaccine, according to a presentation at the American
Headache Society's 2021 annual meeting.
Some
COVID-19 Survivors Experiencing Distorted Food Smells: Some people who’ve recovered from
COVID-19 say they’ve lost their sense of smell or experienced distorted scents,
especially with food. Experts say this ailment can affect people’s ability to
taste food and do daily tasks. It can even affect people’s moods. There are few
treatments for the disorder, although some aroma therapies may help. Healthline
Delta
Becomes Dominant Coronavirus
Variant in US: The contagious delta variant has become the dominant form
of the coronavirus in the U.S., now accounting for more than 51% of COVID-19
cases in the country, according to new CDC
data. Communities with low vaccination rates are bearing the brunt of new
delta cases. Public health experts are urging those who are unvaccinated to get
a shot to protect themselves and their communities against future surges.
mRNA
Vaccines Limit Severity of Rare Breakthrough Infections: In the rare cases of COVID-19 that
occur after vaccination, patients are likely to be sick for less time and have
milder symptoms than if they were unvaccinated, according to a U.S. study of
nearly 4,000 healthcare personnel, first responders, and other frontline
workers. NEJM
Regardless of Health Status, Men Do Worse With COVID-19: Men appear more likely than women to experience severe
outcomes from COVID-19 regardless of whether the men have underlying health
conditions, according to a new study. Researchers in New York City who tracked
roughly 5,000 patients of both sexes who were diagnosed in early 2020 found
that men were sicker when first diagnosed and had a higher need for intensive
care treatment and higher rates of death than women. This was true even though
the men on average were younger and less likely than women to have risk factors
such as obesity and high blood pressure that previously have been linked with
poor COVID-19 outcomes. Communications Medicine
CDC and
Pfizer at Odds Over Need for COVID-19 Booster Shots: Shortly after Pfizer announced its intention to seek FDA
authorization for a third COVID-19 vaccine shot, the CDC, FDA, and NIH
countered with a joint statement the same day saying, essentially, it's still
too soon. In
a battle of the booster shot statements, the vaccine manufacturer and the US
government are drawing very different conclusions based on the evidence to
date.
Long Haul'
COVID Recovery Worse Than Cancer Rehab for Some: CDC: People experiencing
ongoing or "long-haul" symptoms after COVID-19 illness were more
likely to report pain, challenges with physical activities, and
"substantially worse health" compared with people needing
rehabilitation because of cancer, lead author Jessica Rogers-Brown, PhD, and
colleagues report. The study was published
online today in Morbidity
and Mortality Weekly Report (MMWR).
CDC Sees
'New and Concerning Trends' With Delta Variant: The Delta coronavirus strain, now the
dominant variant of COVID-19 in the United States, is surging in areas of the
country with low vaccination rates. CDC Director Rochelle P. Walensky, MD, said
Delta represents a threat to the entire country. "We are starting to see
some new and concerning trends, she said during a White House news briefing.
"Simply put, in areas of low vaccination coverage, cases and
hospitalizations are up. There has also been a spike in cases linked to camping
and community events where prevention strategies "are not enforced,
she said.
Fitbit Stats
Show Lingering Physiologic Hit After COVID-19: People infected with SARS-CoV-2 can
experience lingering physiologic effects after they recover, according to early
data from an ongoing study that is harnessing the power of Fitbits and other
wearable trackers to gauge long-term effects of COVID-19 We found a prolonged
physiological impact of COVID-19 infection, lasting approximately 2 to 3
months, on average, but with substantial intra-individual variability,"Published
online July 7 in JAMA
Network Open.
Extra
COVID-19 Vaccine Could Help Immunocompromised People: People whose immune systems are
compromised by therapy or disease may benefit from additional doses of vaccines
against SARS-CoV-2, researchers say. In a study involving 101 people with solid-organ
transplants, there was a significant boost in antibodies after the patients
received third doses of the Pfizer vaccine. None of the transplant patients had
antibodies against the virus before their first dose of the vaccine, and only
4% produced antibodies after the first dose. That proportion rose to 40% after
the second dose and to 68% after the third dose. The Toulouse University
Hospital findings, published
on June 23 as a letter to the editor of The New England Journal of Medicine
Irregular
Heartbeat Can Be a Lingering Effect of COVID-19: A new study has used wearable devices
and an app to track how long symptoms like low energy, sleep issues, and
elevated heart rate can continue. The researchers found that an elevated heart
rate can last as long as 4 months. The DETECT
studyTrusted Source
Symptoms for
COVID-19, Flu, and Allergies:
COVID-19, the flu, a cold, and allergies have different symptoms. The main
symptoms of COVID-19 are fever, tiredness, cough, and shortness of breath.
Allergies have more chronic symptoms and include sneezing, wheezing, and
coughing. The flu has symptoms similar to COVID-19, such as fever and body
aches, but influenza usually doesn’t cause shortness of breath. If you have a
runny nose or itchy eyes, it doesn’t mean you have the coronavirus. However, if
you have a cough, fatigue, and a fever, you might have COVID-19. Then again, it could also be the seasonal
flu. Check with your local health department about testing, vaccination and
what symptoms they are seeing that are associated with Covid.
Large
Remdesivir Study Finds No COVID-19 Survival Benefit
Early
Heparin Treatment Linked to Lower COVID-19 Mortality
Statins,
used to reduce cholesterol may reduce Covid-19 severity: Using anonymized medical records from a
national registry, researchers confirmed earlier findings that statins may
substantially minimize adverse outcomes from SARS-CoV-2 infection. Plos One
PAIN
Connection Between Migraine, Rheumatoid
Arthritis: A new
study confirms what people with rheumatoid arthritis have already
suspected. people with migraine are more likely to develop this type of
arthritis. And, on the flip side, people with RA are also more likely to
develop migraine.
Fatty Acids
Found in Fish Can Help Reduce Migraine Pain: According to a new
study published in the BMJ measuring the effects of diet on migraine
frequency and severity in 182 U.S. participants over 16 weeks, a diet that
contains fatty acids found in certain fish- Salmon, tuna, and sardines-can help
reduce the frequency and severity of migraine attacks.
Multimodal
analgesia: The new
'standard of care' for pain control after total joint replacement: a growing
body of evidence supports the use of multimodal analgesia - combinations of
different techniques and medications to optimize pain management while reducing
the use and risks of opioids, according to a paper in The Journal of Bone & Joint
Surgery.
Western high-fat diet can cause chronic pain:
A typical Western high-fat diet can increase the risk of painful disorders
common in people with conditions such as diabetes or obesity. Moreover, changes
in diet may significantly reduce or even reverse pain from conditions causing
either inflammatory pain - such as arthritis, trauma or surgery - or
neuropathic pain, such as diabetes. The novel finding could help treat
chronic-pain patients by simply altering diet or developing drugs that block
release of certain fatty acids in the body. Nature Metabolism
COMPLEMENTARY & ALTERNATIVE MEDICINE
People with
fibromyalgia substituting CBD for opioids to manage pain: In a study of almost 900 people with
fibromyalgia, 70% who used CBD substituted CBD for opioids or other pain
medications. Of these participants, many reported that they either decreased
use or stopped taking opioids and other pain medications as a result. The
Journal of Pain
New Study
Linking Cannabis to Suicidal Thoughts:
According to the findings, which published in JAMA Network Open this week,
even people who used marijuana sporadically were more likely to have depression
than those who didn’t use marijuana at all. People with underlying mental
illness who have a pre-existing risk for suicide ideation may be more likely to
use marijuana to treat their symptoms.
It’s unclear if marijuana directly increases a person’s risk of mental
illness and suicide ideation. Experts say more research is needed to better
understand the link.
Mindfulness
therapy may help bring on the zzz's
The randomised controlled study compared a Mindfulness-Based Therapy for
Insomnia (MBTI) with an active Sleep Hygiene, Education, and Exercise Programme
(SHEEP) to see if the former could improve sleep outcomes in older adults with
sleep complaints. A total of 127 participants, aged 50-80, were randomised and
allocated between the two programmes - 65 received MBTI while 62 went through
SHEEP. Both interventions consisted of eight weekly sessions which were of two
hours duration each. Although sleep quality improved across the board, the
study found MBTI to be more effective in reducing insomnia symptoms than SHEEP.
Psychological Medicine
FDA ACTION
• Approved
the use of Astepro, an over-the-counter nasal antihistamine, to treat allergy
symptoms.
• Approved
Rylaze (asparaginase erwinia chrysanthemi (recombinant)-rywn) as a component of
a chemotherapy regimen to treat acute lymphoblastic leukemia and lymphoblastic
lymphoma in adult and pediatric patients
• Approved
emergency use authorization of Actemra (tocilizumab) for the treatment of
hospitalized adults and pediatric patients with COVID-19
PREVENTION:
Exercise
Can Aerobic
Exercise Improve Cognitive Function and Decrease Alzheimer's Disease Risk? A
new study
has found evidence that one year of aerobic exercise training improved
cardiorespiratory fitness, cerebral blood flow regulation, and memory function
in people with mild cognitive impairment.
Dancing to
music may halt progression of Parkinson’s disease: The
results of a new study suggest that dancing to music can halt the progression
of physical and psychological symptoms of Parkinson’s. Brain Sciences.
Taking the
brain out for a walk: If
you're regularly out in the fresh air, you're doing something good for both
your brain and your well-being. This is the conclusion reached by a longitudinal
study. The World Journal of Biological Psychiatry.
High
Physical Activity levels may counter serious health harms of poor sleep: Physical activity levels at or above
the weekly recommended amounts may counter the serious health harms associated
with poor sleep quality, suggests a large long term study. Recommended physical
activity level is 150 minutes of moderate intensity activity or more than 75
minutes of vigorous intensity activity a week. Sleep of 0-5 hours was considered
poor. British Journal of
Sports Medicine
PREVENTION:
Vitamins/Supplements
Supplements
for Weight Loss: Do They Work?
A new comprehensive study published in the journal ObesityTrusted Source on June 23 has found
that dietary supplements do not result in dramatic weight loss as they
claim. In fact, it’s rare that people
who take these supplements lose any weight, the research showed. Journal of
Applied Physiology
Dietary Supplements for Headaches:
Several dietary supplements, including riboflavin, coenzyme Q10, and the herbs
butterbur and feverfew, have been studied for headaches and migraine, with some
promising results in preliminary studies. However, more rigorous studies are
needed before definitive conclusions can be drawn. NCCIH Clinical Digest
PREVENTION: Diet/Nutrition
Cup of
Coffee May Lower Your Risk of Liver Disease: The study, which published in the journal BMC Public Health on
June 22, found that coffee drinkers had a 21 percent reduced risk of liver
disease and a 49 percent lower risk of death from chronic liver disease. They suspect the health benefits can be
traced to coffee’s anti-inflammatory or anti-fibrotic properties.
Ultra-Processed
Foods May Increase the Risk of Inflammatory Bowel Disease: Researchers say a regular diet that
includes ultra-processed foods increases your risk of developing inflammatory
bowel disease (IBD).Foods such as red meat and salty snacks themselves don’t
necessarily increase the risk. Rather, it’s the way the foods are processed.
You can reduce the amount of ultra-processed foods in your diet by purchasing
products with fewer ingredients and by preparing these foods in your kitchen
where you don’t use as many additives or preservatives. Prospective Urban Rural
Epidemiology (PURE) study The BMJTrusted Source.
Can Eating
Fermented Foods Help Curb Inflammation? A new
study from Stanford School of Medicine suggests that incorporating
fermented foods into the diet may help lower inflammation. Experts say eating
foods that are fermented such as kefir or kimchi (but not alcohol) can improve
overall microbial diversity, which may help lower inflammation.
Eating 3
Servings of Whole Grains a Day May Lower Heart Disease Risk: According to new research
published in The Journal of Nutrition, eating whole grains is associated with
smaller increases in waist size, blood pressure, and blood sugar. This was true
for middle-aged and older adults who ate a minimum of three servings a day.
Those who ate less than one-half a serving a day did not fare as well.
What’s in
Fast-Food Beef, Fish, and Chicken? It’s Not Always 100% Meat:
They can contain additional additives, such as a textured vegetable
protein or a soy product, that make them cheaper to produce. Health experts say these types of processed
meats are less healthy than unprocessed meats. If you’re concerned about the
quality of the meat a fast-food establishment is serving, health experts
suggest checking the ingredients list on the menu, as it may offer unprocessed
options as well as plant-based alternatives. The New York Times investigative report by journalist Julie Carmel was in
response to a class-action lawsuit in California filed back in January against
the fast-food giant.
Switching from Western diet to a balanced diet may reduce skin, joint inflammation: Diet rich in sugar and fat leads to
disruption in the gut's microbial culture and contributes to inflammatory skin
diseases such as psoriasis. Research shows that switching to a more balanced
diet restores the gut's health and suppresses inflammation. ournal of Investigative Dermatology
Study shows
diet causes 84% drop in troublesome menopausal symptoms--without drugs: A new study, published by the North
American Menopause Society in the journal Menopause, found a plant-based
diet rich in soy reduces moderate-to-severe hot flashes by 84%, from nearly
five per day to fewer than one per day. During the 12-week study, nearly 60% of
women became totally free of moderate-to-severe hot flashes. Overall hot
flashes (including mild ones) decreased by 79%.
Starting theday off with chocolate could have unexpected benefits: Eating milk chocolate every day may
sound like a recipe for weight gain, but a new study of postmenopausal women
has found that eating a concentrated amount of chocolate during a narrow window
of time in the morning may help the body burn fat and decrease blood sugar
levels.
New study
links moderate alcohol use with higher cancer risk: A new study has found an association
between alcohol and a substantially higher risk of several forms of cancer,
including breast, colon, and oral cancers. Increased risk was evident even
among light to moderate drinkers (up to two drinks a day), who represented 1 in
7 of all new cancers in 2020 and more than 100,000 cases worldwide. Lancet
Oncology
Lab analysis
finds near-meat and meat not nutritionally equivalent: A research team's deeper examination of
the nutritional content of plant-based meat alternatives, using metabolomics,
shows they're as different as plants and animals. Beef contained 22 metabolites
that the plant substitute did not. The plant-based substitute contained 31
metabolites that meat did not. The greatest distinctions occurred in amino
acids, dipeptides, vitamins, phenols, and types of saturated and unsaturated
fatty acids found in these products. Scientific
Reports
PREVENTION
A low
Omega-3 index is just as strong a predictor of early death as smoking: A new research paper published in the American Journal of Clinical Nutrition
showed that a low Omega-3 Index is just as powerful in predicting early death
as smoking. This landmark finding is rooted in data pulled and analyzed from
the Framingham study, one of the longest running studies in the world.
Metabolism
during sleep: How
does LED and OLED light affect it? A recent study found that organic
light-emitting diodes (OLEDs)
had less of a negative effect on metabolism during sleep compared with LED
light. Journal Scientific Reports
CHEST
releases expert guidelines for lung cancer screening: The American College of Chest
Physicians® (CHEST) recently released a new clinical guideline, Screening for Lung Cancer: CHEST Guideline and Expert Panel
Report. The guideline contains 16 evidence-based recommendations and an
update of the evidence base for the benefits, harms, and implementation of
low-dose chest computed tomography (CT) screening.
New study uncovers how a series of sleep loss impacts mental and physical well being: All it takes is three consecutive
nights of sleep loss to cause your mental and physical well-being to greatly
deteriorate. A new study published in Annals
of Behavioral Medicine looked at the consequences of sleeping fewer
than six hours for eight consecutive nights - the minimum duration of sleep
that experts say is necessary to support optimal health in average adults.
TREATMENT
Pfizer
Pauses Distribution of Stop-Smoking Pill Chantix: Pfizer is suspending distribution of
the anti-smoking treatment Chantix after heightened levels of the carcinogen
N-nitrosodimethylamine (NDMA) were found in some lots of the pills. The
pharmaceutical company is also recalling some lots of Chantix that may have
high levels of NDMA, Reuters
reported. Pfizer told Reuters the
distribution pause was ordered out of abundance of caution while further
testing is conducted.
Upadacitinib Appears Effective Against Atopic Dermatitis in Teens and Adults: Two phase 3, placebo-controlled studies
suggest the oral Janus kinase (JAK) inhibitor upadacitinib is effective for
moderate-to-severe atopic dermatitis (AD), both alone and with topical
corticosteroids. Medscape
Intermittent
fasting no better than calorie restriction for weight loss: Study results suggest that intermittent fasting is no better than
calorie restriction for weight loss and is actually less effective in reducing
body fat content. The
researchers say that including physical activity as part of an intermittent
fasting diet could optimize weight loss. So far, studiesTrusted Source
investigating the dietary practice in humans have found that although it is
safe and effective, it is no more effective than other diets that restrict
calorie intake.
Testosterone
therapy reduces heart attack and stroke: Supplementing testosterone significantly reduces heart
attacks and strokes in men with unnaturally low levels of the hormone,
according to new research presented at the European Association of Urology congress
today. European Association of Urology
Benzodiazepines,
'z-drugs' increase death risk when taken with opioids: A new study of more the 400,000
Medicare patients taking medications for insomnia found that the risk of death
is increased when either benzodiazepines or "z-drugs" are taken with
opioids. PLOS Medicine
Researchers
reduce severity of sleep apnoea by at least 30 per cent: New research published in The Journal of Physiology shows
that researchers have successfully repurposed two existing medications- reboxetine
and butylbromide- to reduce the
severity of sleep apnoea in people by at least 30 per cent.
New advice on arthritis drugs:
New research evaluating the drugs commonly used by
rheumatoid arthritis patients suggests two combinations could reduce the risk
of heart attack and strokes. anti-rheumatic drug regimens that include either tumour
necrosis factor inhibitors or hydroxychloroquine might significantly protect
the endothelium in rheumatoid arthritis. Frontiers in Cardiovascular
Medicine
Antidepressants may improve outcomes in people with diabetes and depression: People with diabetes and depression who
take antidepressants may have a lower risk of death and of serious diabetes
complications, according to a new study. Journal
of Clinical Endocrinology & Metabolism
OTHER
New position statement declares that sleep is essential to health: A new position statement from the
American Academy of Sleep Medicine emphasizes that sleep is a biological
necessity, and insufficient sleep and untreated sleep disorders are detrimental
for health, well-being, and public safety. Journal of Clinical Sleep Medicine